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DSA Quantitatively Evaluated Severe Internal Carotid Artery Stenosis Or The Correlation Analysis Of Occluded Collateral Circulation

Posted on:2020-01-24Degree:MasterType:Thesis
Country:ChinaCandidate:T G WangFull Text:PDF
GTID:2404330572482035Subject:Clinical Medicine
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Objectives:By digital subtraction angiography technology(Digital Subtraction Angiography,DSA),and other imaging studies evaluating intracranial internal carotid artery in patients with acute ischemic stroke in patients with severe stenosis or occlusion open degree of collateral circulation,and discuss the influencing factors of collateral circulation in patients with acute ischemic stroke and collateral circulation influence on prognosis of patients.Methods:Choose from 2016 to 2018,the first hospital in handan city by the imaging diagnosis of severe stenosis or occlusion of internal carotid artery of the 70 cases of patients with acute ischemic stroke,and USES the internal carotid artery DSA evaluation of severe stenosis or occlusion collateral circulation around the openness,divided into collateral circulation open group and collateral circulation is not open,then in accordance with the DSA collateral circulation score will open into open good groups and collateral circulation is poor groups,the basic influence factors of patients after admission and on admission and hospitalization 14 d the United States National institutes of health stroke scale(National Institute of Health stroke scale,NIHSS)and 3 months after treatment the modified Rankin scale(modified Rankin scale,mRS)on correlation analysis of related factors such as age of the patients with high blood pressure,blood fat of coronary heart disease diabetes,smoking history and so on correlation analysis and NIHSS drinking to assess the prognosis and treatment of patients after 14 d after 3 months of mRS score to determine outcomes stroke recovery.Results:Collateral circulation is an independent factor affecting acute ischemic stroke.The Roc curve of collateral circulation was drawn and the critical value was determined;Age,history of hypertension,total cholesterol(CHO),triglycerides(TG),low-density lipoprotein cholesterol(ldl-c),and high homocysteine(Hey)are independent risk factors for open collateral circulation.High density lipoprotein cholesterol(hdl-c)is a protective factor for collateral circulation;The NIHSS score of the group with good collateral circulation opening was significantly lower than that of the group with poor collateral circulation opening at admission and 14 days later.The mRS score at admission and 90 days after admission in the group with good collateral circulation were significantly lower than those in the group with poor collateral circulation at admission.Conclusions:The opening of collateral circulation is influenced by age,Hey,CHO,ldl-c,TG,hdl-c,smoking history,drinking history,etc.,and age,Hcy,CHO,ldl-c,TG,hdl-c are independent influencing factors of collateral circulation opening;Collateral circulation opening can improve the improvement rate of symptoms at admission and treatment after 14 days and functional prognosis after 90 days in patients with acute ischemic stroke;Quantifying collateral circulation according to ROC curve can better predict collateral circulation and evaluate prognosis and functional outcome of acute ischemic stroke.
Keywords/Search Tags:acute ischemic stroke, DSA, quantification, collateral circulation, neurological function
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