| Objective: To analyze the difference of portal vein volume between case group,control group and case group,and explore the diagnostic value of MSCTA portal vein volume measurement in cirrhosis with portal hypertension and esophageal varices.Methods:Patients with cirrhotic portal hypertension diagnosed by other clinical examinations and Philips 256-slice spiral iCT in our hospital from January to December 2018 were enrolled.All 81 patients who underwent abdominal CTA examination patients as the case group.There were 60 cases of posthepatitis B cirrhosis,4 cases of hepatic cirrhosis after hepatitis C,3 cases of autoimmune cirrhosis,4 cases of biliary cirrhosis,10 cases of alcoholic cirrhosis;50 cases with ascites,36 cases with esophagogastric variceal bleeding.There were 64 males and 17 females in the case group.According to the Child-Pugh classification of liver function,there were 20 cases of grade A,38 cases of grade B,and 23 cases of grade C in the case group.Esophageal varices occurred in 69 patients.According to the extent and extent of esophageal vein distortion in abdominal CTA,esophageal varices in patients with portal hypertension were divided into three grades,including 12 grade I,29 grade II and 28 cases of grade III.Patients in the case group with esophagogastric variceal bleeding in this study completed abdominal CTA examination withintwo weeks after the first hemorrhage.In the same period of time,20 patients with no portal hypertension were included in the clinical and imaging examinations,including 13 males and 7 females.In this study,the portal vein volume is defined as the sum of the three-dimensional volume of the portal vein,the left and right branches of the intrahepatic portal vein,and the splenic vein.All the examiners in the case group and the control group obtained the portal vein volume using the Philips Portal post-processing workstation;the difference in portal vein volume between the case group and the control group was compared;the portal vein volume was compared with the age in the case group;the post-viral hepatitis type B cirrhosis in the case group was compared with other types of cirrhosis;comparison of portal vein volume differences in patients with different Child-Pugh grades;comparison of portal vein volume differences in patients with or without history of esophagogastric variceal bleeding in the case group;The difference in portal vein volume in patients with ascites;the presence or absence of esophageal varices in the case group and the difference in portal vein volume in patients with different grades.Results:(1)The difference in portal vein volume between the case group and the control group was compared by two independent samples t-test.The difference between the groups was statistically significant(P<0.05).(2)Pearson linear correlation coefficient was used to compare the correlation between portal vein volume and age in the case group,P=0.581,correlation coefficient r=-0.062,and there was no correlation between them.(3)The case group was compared with portal vein volume of post-viral hepatitis type B cirrhosis and other causes of cirrhosis with portal hypertension.The t-test of two independent samples was used,the difference was statistically significant(P=0.031).(4)The difference of portal vein volume in the Child-Pugh Class A,B and C patients in the 4 case group was analyzed by one-way ANOVA with multi-sample mean comparison.The difference between the groups was statistically significant(P=0.002);further two comparison.There were significant differences between the two groups(P<0.05).(5)The differences in portal vein volume between the bleeding group and the non-bleeding group were analyzed by t-test of two independent samples(P=0.002).(6)The difference of portal vein volume between the ascites group and those without ascites was compared by two independent samples.The difference was statistically significant(P<0.05).(7)Cases of abdominal CTA with or without esophageal varices and esophageal varices were compared with different grades of portal vein volume.One-way ANOVA of variance was used for multi-sample mean comparison.There was no significant difference between the two groups(P>0.05).There was no significant difference between the groups(P>0.05).Conclusion:(1)MSCTA portal vein volume measurement has certain value for the diagnosis of portal hypertension.(2)Portal vein volume measurement has certain value for suggesting theetiology of portal hypertension,Child-Pugh classification and prediction of esophageal variceal bleeding.(3)The measurement of portal volume is limited in the diagnosis of esophageal varices and esophageal varices. |
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