| Objective To evaluate the clinical effect of EnSite mapping-guided radiofrequency ablation for patients with idiopathic ventricular premature beats arising from right ventricular outflow tract(RVOT-VPBs)and its influence on myocardial injury.Methods The clinical data of 84 patients with RVOT-VPBs who underwent radiofrequency ablation in our hospital from January 2013 to January 2016 were retrospectively analysed.The patients were divided into conventional treatment group(n=50)who received radiofrequency ablation guided by electrophysiological mapping,and EnSite group(n=34)who were treated by EnSite mapping-guided ablation.Compared the duration of mapping,radiofrequency ablation,X-ray exposure and operation of the two groups.The success rate,recurrence rate,complication rate and the magnitude of myocardial injury of the two groups were statistically analyzed.ECG and ablation characteristics of the right ventricular outflow tract premature beats were analyzed,and their efficacy and safety were evaluated.ResuIts Compared with the conventional group,the duration of mapping,radiofrequency ablation,X-ray exposure and operation were significantly decreased in the EnSite group(P<0.05).Preoperatively,there was no statistically significant difference in VPBs between the two groups.After the operation,the VPBs in the EnSite group was significantly lower than that in the conventional group at 24h(P<0.05).Parameters including creatine kinase(CK),creatine kinase isoenzyme MB(CK-MB),cardiac troponin T(cTnT),aspartate aminotransfbrase(AST),lactate dehydrogenase(LDH),myoglobin(Mb)and hydroxybutyrate dehydrogenase(HBDH)were signficantly lower in the EnSite versus conventional group at 72h(P<0.05).ConcIusion EnSite mapping-guided radiofrequency ablation remarkably decreases the operation time and alleviate the myocardial injury,which is beneficial for patients with RVOT-VPBs. |