| Objective:To assess the incidence of hearing impairment by aligning 651 infants with hearing rescreening in Qiqihar City,and to explore the influencing factors of hearing screening failure.Methods The study subjects were the first time that the newborn hearing screening was performed in a hospital in Qiqihar City from.Methods:In this study,January to May 2017,and the newborns in our hospital were screened.A total of 651 cases were routinely screened.Hearing identification: The first step is to use the distortion product otoacoustic emission(DPOAE)+Automatic auditory brainstem response(AABR)for initial diagnosis,and to enter the second step(determine diagnosis),including auditory brainstem response,for those who have not passed the initial diagnosis.Multi-frequency auditory steady-state response(ASSR)for audiological assessment and identification,assisted high-resolution CT scan of the tibia if necessary.Close follow-up was performed for all cases.Through the "Zhongxin Women and Children Information System" and questionnaire survey,the basic information of the baby at birth and the maternal pregnancy status were collected.Results:(1)A total of 651 infants and young children underwent hearing screening from January 2017 to December 2017 in a hospital in Qiqihar City.All selected infants were screened for audiological composition and 271 cases of hearing abnormalities were diagnosed.The failure rate was 41.63.Among the 101 cases in which DPOAE+AABR failed,51 cases had abnormal hearing of one ear and 50 cases had abnormal hearing of both ears.Of the 66 patients who had failed DPOAE through AABR,32 had abnormal hearing errors in one ear and 34 had hearing abnormalities in both ears.Among the 104 cases in which DPOAE did not pass AABR,there were 60 cases of abnormal hearing in one ear and 44 cases of hearing abnormality in both ears.(2)26 cases of deafness genes were detected in 651 newborns,and the detection rate was 4.0%.Among them,14 cases were detected by male infants,3.75%(14/373),and 12 cases were detected by female infants.The detection rate was 4.32%(12/278).Among them,26 cases were detected by GJB2,and the detection rate was 4%.No abnormalities were found in other genes.(3)558 cases of term infants,93 cases of premature infants,208 cases(37.3%)of full-term children in the hearing screening group,63 cases(67.8%)of premature infants,the difference was statistically significant(p<0.05)There were 264 cases of 651 neonates with 196 cases(74.2%),387 cases of cesarean section,and 75 cases(19.4%).The difference was statistically significant(p<0.05).There were 39 cases of gestational diabetes in pregnant women,28 cases(71.8%)failed,612 cases of gestational diabetes,and 243 cases(39.7%),the difference was statistically significant(p>0.05);576 cases of asphyxia did not appear.There were 75 cases of asphyxia;3 cases of asphyxia in the hearing screening group,377 cases of asphyxia did not appear,the difference was statistically significant(p<0.05);651 cases of neonatal low-weight children 51 cases,failed 36 cases(70.6 %);600 normal weight children,235 cases(29.2%),the difference was statistically significant(p<0.05);57 cases of hyperbilirubinemia in neonates,55 cases(96.5%)There were 594 cases of gestational diabetes mellitus and 216 cases(36.4%)were not passed,the difference was statistically significant(p<0.05).(4)Multi-factor analysis of failed parental rescreening in infants and young children showed that pregnant mothers with prenatal hemorrhage,low birth weight infants,asphyxia,hyperbilirubinemia,and premature infants and pregnant mothers were affected by hearing rescreening.Conclusion:1.The children in this study were rescreened with DPOAE and AABR,and combined with the examination,which helped to improve the accuracy of hearing screening.In 651 infants and young children who were undergoing hearing screening in a hospital in Qiqihar in 2017,none of them passed.In 271 cases,the rate of failure was 41.63%.2.In this study,26 cases of common deafness genes were detected in 651 hearing-reporting infants in a hospital in Qiqihar City,the detection rate was 4%,and the abnormal genes were all c.235 delC sites of GJB2.3.Factors related to the failure of infants and young children's hearing screening,mainly pregnant mothers with prenatal bleeding,asphyxia,hyperbilirubinemia,etc.,clinical attention should be paid to newborns with high risk factors to ensure early diagnosis of early intervention. |
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