Prognostic Significance Of Pretreatment Serum Hemoglobin Level In Early Extranodal Nasal Type NK/T Cell Lymphoma

Objective:To investigate the effect of pretreament serum hemoglobin(Hb)level on the prognosis of early extranodal nasal type NK/T cell lymphoma.Methods:Records of patients with extranodal nasal type NK/T cell lymphoma,treated in Shanxi Medical University Affiliated Tumor Hospital from 2000 to 2015,were reviewed.The inclusion criteria including Ann Arbor I/II stage,the primary tumor site located in the upper aerodigestive tract,not with other malignant diseases and complete clinical information and follow-up data.Results:Of the 218 cases,175 cases were involved in the analysis according to the inclusion criteria.In univariate analysis,the pretreatment serum Hb level(?120 g/L),LDH level(normal),ECOG performance status(0-1),Ann Arbor(I_E)and radiotherapy significantly improved Progression free survival(PFS)and Overall survival(OS).In multivariate analysis,the pretreatment serum Hb level,LDH level,ECOG performance status and Ann Arbor stage are independent prognostic factors for PFS and OS.Conclusions:Patients with pretreatment serum Hb level?120 g/L have a better prognosis than those with<120g/L.