Clinical Analysis Of Neck Treatment Of Gingival Squamous Cell Carcinoma On CN0

Objective: Through the retrospective analysis of 51 cases of clinical data,the occult metastasis of cervical lymph nodes in cN0 squamous cell carcinoma and its influencing factors were discussed,which provided the basis for clinical treatment of cN0 upper gingival squamous cell carcinoma.Methods:The data of patients with cN0 gingival squamous cell carcinoma who were admitted to the Oral and Maxillofacial Surgery Department of the Fourth Hospital of Hebei Medical University between January 2010 and January 2017 were collected.All the patients underwent primary tumor resection,and postoperative pathology confirmed upper gingival squamous cell carcinoma.A total of 51 people met the criteria for inclusion in this study.There are 25 males and 26 females,aged between 25 and 81 years old,with a median age of 65 years.SPSS22.0 statistical software was used to analyze the clinical and pathological factors related to cervical lymph node metastasis by Chi-square/Fisher test.Logistic multivariate regression analysis was used to analyze independent factors.The difference was statistically significant at P<0.05.Result:Univariate statistical analysis showed that the cervical metastasis of gingival squamous cell carcinoma on cN0 was significantly associated with the size of the primary tumor and the depth of tumor invasion(P<0.05),with sex,age,pathological differentiation,primary tumor location,growth pattern,and 2 Type 2 diabetes had no significant correlation(P>0.05).The multivariate statistical analysis showed that the primary tumor size was an independent factor.Conclusions:1.The size of the primary tumor is an independent influencing factor of neck metastasis of gingival squamous cell carcinoma on cN0.The upper cingulated squamous cell carcinoma of cN0 with a primary tumor diameter of >4cm needs selective neck dissection(?-?)at the same time.The diameter of the primary tumor is ? 4cm should be followed closely.2.The gingival squamous cell carcinoma of cN0 with lesions invading the muscularis and jaw bone should undergo selective neck dissection(?-?)at the same time.Infiltration of gingival squamous carcinoma of cN0 in the mucosal layer can be followed closely.3.Cervical metastasis of gingival squamous cell carcinoma on cN0 was not related to gender,age,pathological differentiation,location of primary tumor,growth pattern,and type 2 diabetes.