The Imaging Features Of The Ground Glass Nodules In The Lung And The Correlation Between Benign And Malignant Tumors Analysis

Objective: In this paper,the relationship between the characteristics of the nodules and the benign and malignant tumor of the lung is analyzed,and the strategies and methods of evaluating pulmonary nodules in clinical practice are discussed.Research methods: We had a retrospective review of 182 GGNs having a fnal diagnosis in the department of thoracic surgery,from January 2016 to December 2017,and analyzed their clinical data and computed tomography(CT)images,including age,gender,smoking history,family history of cancer,previous cancer history,nodule location,lobulation,spiculation,vascular convergence,pleural retraction sign,air bronchogram sign,vocule sign,the largest diameter of the solid part(C),the largest diameter of the ground glass part(T)and C/T.By using univariate analysis,we found the independent predictors of malignancy of GGNs.Receiver-operating characteristic(ROC)curves were constructed using the prediction model.Results: in 182 patients,the median age is 61(61.9±9.1),the minimum age is 35 and the maximum age is 82.Among them,there are 87 males(47.8%)and 95 females(52.2%).Univariate analysis shows gender(p=0.003),smoking history(p=0.008),lobulation(p=0.009),spiculation(p=0.000),vocule sign(p=0.001),pleural retraction sign(p=0.003),the largest diameter of the solid part(C)(p=0.000)and C/T value(p=0.000)have a statistical difference.While age(p=0.699),family history of cancer(p=0.44),previous cancer history(p=0.058),vascular convergence(P=0.319),air bronchogram sign(p=0.571),the largest diameter of the ground glass part(T)(p=0.186)don't have a statistical difference.The sensitivity and specificity of the benign nodules and malignant nodules were best when the maximum diameter of the longitudinal cross-section was 18.7mm,the sensitivity is 66.4% and specificity is 89.7%.The sensitivity and specificity of the benign nodules and malignant nodules were best when C/T value was 78.7%,the sensitivity is 93.6% and specificity is 70.2%.Conclusion: Between the Benign and malignant groups,gender,smoking history,nodule location,lobulation,spiculation,pleural retraction sign,vocule sign,the largest diameter of the solid part(C)and C/T value have a statistical difference.Analysis of the largestdiameter of the solid part(C)and C/T value could accurately identify malignancy in patients with solid SPNs,thereby it can provide help for diagnosis of GGNs.