The Analysis Of Fluid And Electrolyte Disorders In 159 Patients With Pituitary Adenoma After Transsphenoidal Surgery

Objective: Pituitary adenoma is one of ordinary intracranial tumor.The common procedure for treating is transsphenoidal surgery,which is classified as endoscopic transsphenoidal surgery(ETS)and microscopic transsphenoidal surgery(MTS).Postoperative complications such as fluid and electrolyte disorders,diabetes insipidus are familiar.To discuss the appearance of postoperative fluid and electrolyte disorders by analyzing its conditions is our primary objective.Method: :In this study,159 patients with pituitary adenoma treated by neurosurgery in the first hospital of China medical university were selected through sample control and statistical analysis.Results: 1.Diatebes Insipidus is more likely to lead to electrolyte disorder 2.Microscopic transsphenoidal surgery has lower rates than microscopic transsphenoidal surgery in appearance of diabetes insipidus 3.The shift of the pituitary stalk is more likely to trigger the electrolyte disorders 4.The size of the tumor(large adenoma vs.large adenomas),whether to have endocrine function has no obvious correlation with the incidence of ion electrolyte disorders.Conclusion: 1.Microscope transsphenoidal surgery approved controversial on the issue of postoperative diabetes insipidus compared with endoscopy 2.Our center's incidence of postoperative diabetes insipidus in domestic average level,above the level of the foreign(3)the occurrence of electrolyte disorders may be associated with the interference of the cerebal saltwasting syndrome and inappropriate secretion of antidiuretic hormone syndrome 4.Tumor on the endocrine function of interference is not enough to affect water and electrolyte balance,and may be the cause of the hypothalamus paraventricular nucleus dysfunction.