The Diagnostic Value Of C-TBNA And EBUS-TBNA In Mediastinal Hilar Occupational Lesions And EBUS-GS-TBLB In Peripheral Pulmonary Nodules

Objective To evaluate the diagnostic values and safeties of conventional transbronchial needle aspiration(C-TBNA)and endobronchial ultrasound-guided transbronchial needle(EBUS-TBNA)in mediastinal hilar occupational lesions and endobronchial ultrasound-guided transbronchial lung biopsy(EBUS-GS-TBLB)in peripheral pulmonary nodules.Methods A total of 155 patients with thoracic CT examinations showed mediastinal,hilar lymphadenopathy or peripheral pulmonary nodules in the Department of Respiratory and Critical Care Medicine,Guizhou Provincial People’s Hospital from December 2011 to December 2017,were divided into three groups:63 patients undergoing C-TBNA examination(Group A),69 patients undergoing EBUS-TBNA examination(Group B),23 patients undergoing EBUS-GS-TBLB examination(Group C).The results of cytology or pathology were analyzed in the three groups.Results In group A,24 cases were malignant tumors and 8 cases were benign diseases,with the positive rate of 51.1%.In group B,36 cases were malignant tumors and 13 cases were benign diseases,with the positive rate of 71%.There was statistically significant difference in positive rate between Group A and Group B(P<0.05).In the malignant tumor cases of the two groups,the most puncture sites are 4 group and 7 group lymph nodes in chest.In the Group C,11 cases had positive result and positive rate was 47.8%,7 cases were malignant tumors,4 cases were benign diseases.All patients in three groups had no serious complications.Conclusion The overall positive rate of EBUS-TBNA in patients with mediastinal and hilar lesions is higher than C-TBNA.Moreover,C-TBNA and EBUS-TBNA have higher positive rate in central group lymph nodes(4 group,7group)than peripheral group lymph nodes(10group,11group)for the malignant tumor diagnose or staging.All three technologies are safe.