| ObjectiveThrough the elaborate-moxibustion,grain-sized moxibustion of depression related insomnia clinical evaluation of the two moxibustion treatment of depression-related insomnia differences in efficacy.MethodsVolunteers conforming to the inclusion criteria of depression-related insomnia were recruited in the acupuncture department of Guangdong Province Hospital of Traditional Chinese Medical.The selected acupoints were the same in 2 groups.Acupoints seleting:(1)BL13,BL15,BL18,BL20,BL23.(2)CV13,CV10,CV6,CV4,ST23,BL17,BL19.Choose a group of acupuncture points for each treatment,two groups of acupuncture points to use.In the acupoints,the skin was topped with kava oil and placed in the Ai Miao group.The moxa moxibustion group was used small moxibustion(bottom diameter 2mm and height 3mm).The grain-sized moxibustion group was used grain-shape moxibustion(bottom diameter 5mm and height 8mm).Since the tip with incense light incense.Moxa burning to the remaining about one-third of patients with slight redness of the skin,slight pain when removing moxa,each hole with moxibustion 2 moxa.Two treatment interval more than 48 h,2 times a week,a course of 10 times.Respectively before treatment,the end of treatment,follow-up of 1 month a total of 3 time points for evaluation.The Pittsburgh Sleep Index(PSQI)and Hamilton Depression Rating Scale(HAMD-24)were used as the main indexes.The questionnaire of health status of patients(SF-36),safety evaluation and adverse reaction evaluation were taken as secondary observation indexes.Use SPSS 18.0 statistical software package to make database,carry out data cleaning and statistical analysis.P <0.05 as a significant level.Intentional analysis of exfoliated case data.The metrological data is expressed as(mean ± standard deviation)and the count data is expressed as frequency and ratio.Baseline,the measurement data using analysis of variance or non-parametric test,count data using chi-square test;grade data comparison between groups using non-parametric test.Multi-point comparison of measurement data using ANOVA of repeated measurement data.Result1.The study finally included 61 cases of effective cases,including 30 cases of fine moxibustion group,31 cases of moxibustion group.2.Baseline:Two groups of patients age,gender,education,occupation and other baseline data were no difference,they had comparability.3.PSQI scale:In the elaborate-moxibustion group and the grain-sized moxibustion group,the scores at each time point after treatment decreased compared with those before treatment,and the scores were statistically significant before treatment(P<0.05).At the end of treatment,the scores of elaboratemoxibustion group and the grain-sized moxibustion group were statistically significant(P=0.015).At one month follow-up,the scores of elaboratemoxibustion group and grain-sized moxibustion group were statistically significant(P=0.017).4.HAMD-24 scale:In the elaborate-moxibustion group and the grain-sized moxibustion group,the score at each time point after treatment decreased compared with that before treatment,and the decreasing amplitude was statistically significant(P=0.000).At the end of treatment,the scores of elaboratemoxibustion group and the grain-sized moxibustion group were statistically significant(P=0.010).At 1 month follow-up,the scores of the moxibustion group and the moxibustion group were statistically significant(P=0.008).5.SF-36 scale:(1)Intra-group comparison:The scores of BP,GH,and VT in the elaborate-moxibustion group increased at each time point after treatment compared with before treatment,and the difference was statistically significant(P<0.05).In the SF dimension,the score was increased compared with before treatment at the end of treatment.The difference was statistically significant(P<0.05).There was no significant difference in the PF,RP,RE,and MH dimensions at each time point(P>0.05).There was a statistically significant difference between the scores of the grain-sized moxibustion and VT on the GH and VT dimensions before treatment(P<0.05).On the BP dimension,the scores on the BP dimension increased after the treatment was compared with that before the treatment.The differences were statistically significant.Significance(P<0.05).There was no statistically significant difference in the PF,RP,SF,RE,and MH dimensions(P>0.05).(2)Comparison between groups:On the PF,RP,SF,RE,and MH dimensions,there was no statistically significant difference between the elaborate-moxibustion group and the grain-sized moxibustion group at each time point after treatment(P>0.05).In the BP and GH dimensions,the difference between the elaboratemoxibustion group and the grain-sized moxibustion group at the end of treatment was not statistically significant(P>0.05).In the follow-up at 1 month,the score of the elaborate-moxibustion group was higher than that of the grain-sized moxibustion group.Statistical significance(P<0.05).In the VT dimension,the scores of the elaborate-moxibustion group at each time point after treatment were higher than those of the wheat grain-sized moxibustion group,and the difference was statistically significant(P<0.01).6.Efficiency:The total effective rate of elaborate-moxibustion group and grain-sized moxibustion group was 93.33% and 77.42% respectively.The difference was statistically significant(Z=-2.408,P=0.018).7.Adverse reactions:In this study,there were 3 cases of adverse events,all showed for the treatment of local small blisters,are mild adverse reactions,are related to this study,without special treatment,can relieve itself,suggesting that operators should be careful operation.Elaborate-moxibustion is a safe treatment,adverse reactions less.ConclusionThe effect of elaborate-moxibustion and grain-sized moxibustion on improving sleep quality,depressive symptoms and quality of life in patients with depression-related insomnia were all effective,the effect of elaborate-moxibustion was better than grain-sized moxibustion. |
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