Risk Factors For Allogenic Transfusion After Posterior Correction Surgery For Adolescent Idiopathic Scoliosis:A Prospective Observation Analysis

Objective To investigate the incidence and risk for allogenic transfusion after posterior correction surgery for adolescent idiopathic scoliosis.Methods We retrospectively analysis 936 patients(147 males,789 females)undergoing posterior correction surgery for adolescent idiopathic scoliosis from January 2012 to December 2016.Average age of included patients were 14.4±1.7 years old(11-18).Patient number?name?sex?age?the preoperative hemoglobin?preoperative creatinine?preoperative BUN?preoperative coagulation markers?preoperative cobb angle?ASA score?BMI?intraoperative estimated blood loss?operation time?osteotomy?TXA?number of fused levels?postoperative drainage volume were collected.Potential risk factors for postoperative allogenic transfusion were evaluated by univariate and multivariate regression analysis.Results Postoperative allogenic transfusion was performed 188(20.1%)patients undergoing posterior correction surgery for adolescent idiopathic scoliosis.Univariate analysis showed that preoperative hemoglobin?preoperative cobb angle?BMI?intraoperative estimated blood loss?operation time?TXA?number of fused levels?postoperative drainage volume?ASA score?sex had significant effects on postoperative allogenic transfusion.Logistic regression analysis identified male(OR=2.258?95%[CI]:1.266-4.028)the number of fused levels to be more than 12(OR=1.587?95%[CI]:1.070-2.353)?preoperative hemoglobin lower than 128 g/L(OR=1.956?95%[CI]:1.356-2.820)?postoperative drainage volume more than 515ml(OR=2.025?95%[CI]:1.409-2.911?the use of TXA(OR=0.497?95%[CI]:0.266-0.930)as influencing factors for postoperative allogenic transfusion.Conclusion The allogenic transfusion rate after posterior correction surgery for adolescent idiopathic scoliosis was 20.1%.The number of fused levels?preoperative hemoglobin?male?postoperative drainage volume?TXA are factors influencing postoperative allogenic transfusion.