Two Kinds Of Surface Treatment Of Titanium Implant Ion Release In Vivo Studies

Objectives: Discusses embedded sandblasting acid corrosion electrochemical anodic oxidation and large particles implant two kinds of surface treatment of titanium ion release in different periods.Methods: 1.Pull out five experimental dogs under general anesthesia on both sides of the mandibular second and third premolar,using inductively coupled plasma mass spectrometry(icp-ms,ThermoFisher)each experimental dogs gums,alveolar bone and titanium ion concentration in peripheral blood.2.3 months after tooth extraction,under general anesthesia in 5experimental dogs only on both sides of mandibular deficiency in the area and bilateral tibial anterior medial 1/3 place implants were implanted into two surface treatment,postoperative 1,2,3 months respectively using inductively coupled plasma mass spectrometry(icp-ms,ThermoFisher)on both sides of each experimental dogs,bones,gums and peripheral blood of titanium ion concentration.Results: 1.The embedded sandblasting acid corrosion electrochemical anodic oxidation and large particles surface treatment after implant,gum fromgrowing titanium ion concentration in the preoperative 7.52±1.71 mg/kg higher electrochemical anodic oxidation group was 39.92±1.14 mg/kg,larger particles sandblasting acid corrosion group was 29.50 ±2.75 mg/kg;Bones of titanium ion concentration from growing preoperative 484.20±86.35 mg/kg higher electrochemical anodic oxidation group was 763.00±104.28 mg/kg,larger particles sandblasting acid corrosion group was 724.20±33.98 mg/kg;Titanium ion concentration in the blood from the planting technique of 7.18 ± 0.19mg/kg increased to 10.43±0.76 mg/kg,postoperative preoperative rise by 1.5times.2.Embedded sandblasting acid corrosion electrochemical anodic oxidation and large particles surface treatment after implant,gum electrochemical anodic oxidation in postoperative 1 month group17.28±1.71 mg/kg larger sandblasting particles acid group 19.50±1.04 mg/kg,2,3 months after electrochemical anodic oxidation group is rapidly rising,electrochemical anodic oxidation group39.92±1.14mg/kg larger sandblasting particles acid group 29.50±2.75mg/kg;Bone in postoperative 1 month electrochemical anodic oxidation group585.40±16.80 mg/kg larger sandblasting particles acid group 647.40±80.46mg/kg,2,3 months after electrochemical anodic oxidation group is rapidly rising,electrochemical anodic oxidation group 763.00±104.28 mg/kg larger sandblasting particles acid group 724.20±33.98 mg/kg.3.Electrochemical anodic oxidation and larger particles implanted implant sandblasting etched surface treatment after 3 months,there are differences between the concentration of titanium ion concentration between different organizations,the gum of titanium ion concentration detection average was34.71±5.84 mg/kg,the bones of titanium ion concentration detection average was 743.60 ±75.92 mg/kg,titanium ion concentration in the blood test averageof 10.43±0.76 mg/kg,according to the results of titanium ion concentration detection average bone above the gum and blood.Conclusion: 1.In the cultivation of early postoperative existing titanium ion released into the surrounding tissue,enrichment concentration higher than gum in bone and blood and accumulated gradually increased over time.2.Electrochemical anodic oxidation surface treatment larger sandblasting particles acid corrosion of the surface treatment by high concentration of titanium ion release.