Prevalence And Related Factors Of Lower Extremity Arterial Disease In Hospitalized Patients With Type 2 Diabetes Mellitus

Objectives: To understand the prevalence of lower extremity arterial disease(LEAD)in hospitalized patients with type 2 diabetes mellitus(T2DM)and to explore the risk factors associated with its occurrence;evaluate the understanding of LEAD patients in this disease;Find controllable factors to prevent LEAD.Methods: The clinical data of 266 patients with type 2 diabetes who were examined in the Department of Endocrinology Hospital Affiliated Hospital of North Sichuan Medical College from January 2016 to June 2016 were collected.Including age,gender,duration of diabetes,body mass index(BMI),systolic blood pressure,diastolic blood pressure,smoking history,drinking history,HbA1 c,fasting blood glucose,postprandial 2-hour blood glucose,blood lipids(high-density lipoprotein,low-density lipoprotein,Triglycerides,Total Cholesterol,Blood Uric Acid,Platelet Count,Mean Platelet Volume,Diabetic Complications,etc.ABI ? 0.9 was used as the diagnostic criteria for lower extremity arterial disease(LEAD),and was divided into the lower extremity arterial disease group(LEAD)group and non-low extremity arterial disease group(non-LEAD)group for general data and related clinical features.Analyze the risk factors associated with LEAD.A unified questionnaire survey was conducted to investigate the awareness of LEAD in the 266 hospitalized T2 DM patients.Evaluate the awareness of lower extremity arterial disease and its risk factors.Results:1?Among the 266 hospitalized patients with type 2 diabetes associated with 73 cases of lower extremity arterial disease(the LEAD),the total prevalence of 27.44%,and its prevalence increases with age.2?Compared with non-LEAD group,patients in LEAD group had older age,longer duration,systolic blood pressure,low-density lipoprotein level,higher proportion of smokers,higher ratio of combined hypertension(p<0.001),and serum uric acid level Higher(p<0.01),higher BMI,MPV,glycated hemoglobin,and triglyceride levels(p<0.05).3?The results of logistic regression analysis showed that smoking history,hypertension,age,systolic blood pressure,triglyceride,and LDL were independent risk factors for LEAD.It has a great relationship with the occurrence of LEAD.4?The rate of awareness of LEAD in hospitalized type 2 diabetes patients in our hospital was 29.3%,and most of the pathways learned were medical staff(92.48%).There was a lack of awareness of LEAD risk factors.Conclusion:The prevalence of arterial disease of lower extremity in T2 DM patients in our hospital is 27.44%,which is higher than that in African countries.It is also higher than that in other economically developed areas in China.It is roughly equal to the incidence of other urban areas in our province.Smoking history,hypertension,age,systolic blood pressure,triglyceride,and LDL were independent risk factors for LEAD.The rate of awareness of LEAD in inpatients with T2 DM in our hospital was 29.3%.There were fewer known pathways and there was a lack of awareness of LEAD risk factors.Therefore,patients should be more aware of LEAD and management education.LEAD screening and diagnosis should be conducted as soon as possible for high-risk groups.Reduce the incidence of diabetic foot.