Prevalence Of Cardiovascular Calcification And Related Factors In Peritoneal Dialysis Patients

Objctive:To explore the incidence of cardiovascular calcification and related factors in peritoneal dialysis patients(PD).Methodology:From December 2013 to August 2014,150 PD patients were enrolled in this study.Laboratory measurements included serum calcium(Ca),phosphorus(P),intact parathyroid hormone(iPTH),and dialysis status were evaluated.Coronary Artery Calcification Score(CACS)was assessed with multi-slice spiral computed tomography(MSCT,Agatston method),Abdominal Aortic Calcification Score(AACS)was assessed with lateral plain radiograph of the abdomen(Kauppila method),echocardiography was used to detect the cardiac valve calcification(CVC).To analyzes related factors of cardiovascular calcification by binary logistic regression.Results:Only 58.0%,46.0%and 23.3%of the 150 PD patients reached the Chinese Society of Nephrology(CSN)defined targets for serum Ca,P and iPTH.The total 57.3%patients had calcification.The prevalence of CAC was 40.7%,AAC was found in 32.7%patients,CVC was presented in 27.3%patients.In addition to the individual groups,the incidence of calcification of any part increased with age,dialysis vintage.Using binary logistic regression,age(Odds Ratio,OR=1.10),dialysis vintage(OR=1.03)were independent risk factors for CAC,but Kt/V as a protect factor(OR=0.27).The independent risk factors for CVC included age(OR=1.07)?serum P(OR=1.94).Conclusion:Although PD patients in this study have low prevalence of cardiovascular calcification(CAC:40.7%,AAC:32.7%,CVC:27.3%),hyperphosphate and abnormal iPTH were still prominent.Age,dialysis vintage and serum P were traditional risk factors for calcification.