| Objective:To investigate the clinical application of one stop imaging of coronary angiography?CCTA?combined with myocardial perfusion imaging?MPI?using 256-slice160mm wide-detector CT in myocardial ischemia of coronary heart disease.Methods:73 cases of suspected or confirmed coronary heart disease patients under-went one-stop coronary artery imaging combined with myocardial perfusion imaging using256 slice CT?detector width 16cm?from January to November 2017.According the standard of SCCT-18 segments,CCTA image quality was evaluated.According the reference of model AHA-17,the myocardial blood flow?MBF?was calculated and compared between that of normal and abnormal segments.Coronary angiography?CAG?as the gold standard,the diagnostic accuracy of CCTA and MPI were evaluated.And the effective radiation dose was counted.Results:Among 73 patients underwent CCTA combined with CT-MPI examination,32patients?43.8%?with 154 myocardial segments?15.9%?were detected blood perfusion coming down,the MBF value was lower than that of normal segments[?71±26?ml·100ml-1·min-1and?113±33?ml·100ml-1·min-1;t=15.971,P=0.000].There were 1026segments?95.5%?whose quality can be used for the diagnosis in CCTA.46 patients were followed up for CAG,and the diagnostic sensitivity,specificity and accuracy of CCTA for CAD were 91.4%?93.2%?93.0%respectively.The diagnostic sensitivity,specificity and accuracy of MPI were 85.3%?83.3%?84.8%respectively.The total effective radiation dose of one stop scanning CCTA combined with CT-MPI was?4.6±1.2?mSv which including the radiation dose of CCTA?2.2±0.6?mSv.Conclusion:Both good CCTA and CT-MPI images can be obtained at the one stop scanning by256-slice 160mm wide-detector CT.In addition to providing morphological information,the functional parameters are added and the diagnostic value ji improved.It has high potential for clinical application. |
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