Analysis Of Risk Factors For Long-term Prognosis Of Acute Pulmonary Embolism

Objective:Acute pulmonary embolism after antithrombotic therapy were followed up,to obtain the long-term prognosis and to find the relevant risk factors that affect the long-term prognosis.Methods:The clinical data of 635 patients with acute pulmonary embolism diagnosed by pulmonary artery(CTPA)or V/Q scan from January 2009 to January 2016 in Qingdao University Affiliated Hospital were retrospectively analyzed.The data of inpatient and outpatient follow-up were retrospectively analyzed.The patients were divided into two groups according to different prognosis:good prognosis group and non-prognosis group.The clinical data of anticoagulation and clinical outcome were analyzed by t-test,X~2 test and non-conditional Logistic regression analysis,and the risk factors influencing long-term prognosis were screened out.Results:A total of 635 cases were included in the clinical trial.After a one-year follow-up,62 patients were lost due to contact changes.A total of 573 patients were followed up by phone,of which 477(83.2%)had a good prognosis.Poor prognosis group 96 cases(16.8%).In the poor prognosis group,32 cases(33.3%)were relapsed,51 died(53.1%)and 16(16.7%)died,of which 3 died of haemorrhage.Unconditional logistic analysis showed that the risk factors affecting the long-term prognosis of patients with pulmonary embolism were Mean diagnosis time(OR:1.045,95%CI:1.011-1.080),malignant tumor(OR:7.536,95%CI:3.451-16.457),idiopathic pulmonary embolism(OR:37.826,95%CI:11.812-121.130),anticoagulation compliance(OR:5.684,95%CI:2.670-12.102),increased BNP concentration(OR:1.002,95%CI:1.001-1.003),and elevated Troponin-I(OR:4.229,95%CI:1.268-14.103).Conclusion:Mean diagnostic time,combined malignant tumor,combined right ventricular dysfunction,idiopathic pulmonary embolism,anticoagulation compliance and elevated BNP and Troponin-T may be risk factors for the long-term prognosis of acute pulmonary embolism.