Objective: To investigate the effect of ultrasound-guided Thoracic Paravertebral Blocks(TPVB)as an Adjunct to General Anesthesia(GA)in anesthesia and analges undergoing thoracoscopic radical surgery for lung cancer.Methods: Fifty patients who underwent thoracoscopic radical surgery for lung cancer were selected and forty-seven of them were included in this study.They were randomly assign to two groups: The experimental group is Thoracic Paravertebral block combined with general anesthesia group(group P)and the control group is General Anesthesia group(group G).group P of thoracic paravertebral block was used after general anesthesia induction,and the two groups were treated with the same intravenous analgesic pump.Mean arterial pressure(MAP)and heart rate(HR)were recorded at times of after entering the operating room(T0),before cut skin(T1),after cut skin(T2),0.5 h after cut skin(T3),1 h after cut skin(T4),1.5 h after cut skin(T5),2.0 h after cut skin(T6).The dose of vasoactive drugs and remifentanil were uesd in surgery,The number of patients with restlessness and sufentanil after extubation.Both resting and coughing visual analogue scales(VAS)were recorded at the points of 30 minutes,six hours,twelve hours,twenty-four hours after operation,and the number of patients who needed the tylenol(aminophenone)was required 24 hours after surgery.Result:Compared with group G,the changes of blood pressure and heart rate after skin incision in group P decreased significantly(P<0.05).The dose of remifentanil needed during the operation was significantly lower than group G(P<0.05).The number of people who were restless and needed sufentanil after extubation was significantly lower than that in group G(P < 0.05).The VAS score in the group P was significantly lower than that in the group G(p < 0.05).Conclusion : Thoracic paravertebral blocks combined with general anesthesia can provide a good analgesic effect and reduce the application of analgesic drugs in thoracoscopic radical surgery for lung cancer. |