The Relationship Between Systemic Lupus Erythematosus Disease Activity Index Scores And Echocardiographic Manifestations Of Heart Damage

Background: Systemic lupus erythematosus(SLE)is a chronic immune connective tissue disease that can affect multiple systems.The disease process is characterized by remission and deterioration that is difficult to control.In SLE patients,more and more reports of heart disease,including changes in the structure and function of the left ventricle.And cardiovascular disease(CVD)is the most common cause of death in SLE patients.More than 50% of patients may have cardiac involvement.SLE patients may develop pericarditis,myocarditis,and arrhythmia.Severe SLE patients may be accompanied by cardiac insufficiency and often indicate a poor prognosis.The Systemic Lupus Erythematosus Disease Activity Index(SLEDAI)is clinically used to evaluate disease activity and outcome in SLE patients.Therefore,this study hoped to further understand the relationship between SLEDAI scores and cardiac dysfunction in SLE patients,aiming at early intervention and improving prognosis.Objective: To evaluate the correlation between SLEDAI scores of SLE patients and related clinical manifestations and echocardiographic manifestations of heart damage.Methods:This retrospective study included 200 patients who were diagnosed with systemic lupus erythematosus from June 2015 to September 2017 in the first Affiliated Hospital of Soochow University,including 13 males and 187 females.The case-control study was to collect clinical data of enrolled patients,and all patients underwent echocardiography within 48 hours after admission.1.According to the SLEDAI scores,patients who met the criteria were divided into two groups: SLEDAI...