Correlative Factor Analysis Of The Formation Of Ventricular Aneurysm After Acute Myocardial Infarctions

Research objective: This study aims to analyse the potential factors that contribute to the formation of ventricular aneurysm(VA)for patients with acute myocardial infractions.Research method: This study investigates a sample of 694 patients who were diagnosed to have got acute myocardial infractions(AMI)and received percutaneous coronary interventions(PCI)in the Department of Cardiology of the First Affiliated Hospital of Soochow University from January 2013 to September 2016.The sample is divided into two groups,with the one group consisting of 59 patients who were confirmed by echocardiography to have developed VA and the other group consisting of 635 patients without VA.With the support of SPSS19.0,a retrospective analysis of the sample is conducted on correlative factors that contribute to the formation of VA,including age,sex,high blood pressure,diabetes,hyperlipidemia,hyperuricemia,smoking,MI history,angina pectoris history,anterior MI,?4 ST segmentation elevation,chest pain time?24 hours,lesion of proximal and mid-left anterior branch,occlusions,single vessel disease,double vessel disease,and multi-vessel disease.Result: 1.Compared with the group without VA,the patients with VA are older and have a higher rate in smoking,anterior MI,?4 ST segmentation elevation,angina pectoris history,chest pain time?24 hours,and lesion of proximal and mid-LAD(P<0.05).2.The single-factor Logistic regression analysis demonstrates that patients with VA have higher occurrences than patients without VA in terms of anterior MI,?4 ST segmentation elevation,chest pain time?24 hours,lesion of proximal and mid-LAD,smoking and age>60(P <0.05-0.01).However,there is no statistical differentiation between the two groups(P>0.05)in terms of sex,MI history,diabetes,high blood pressure,hyperlipidemia,hyperuricemia,occlusions,and vessel diseases(single,double or multi-vessel disease).3.The multi-factor logistic regression analysis proves positive correlations between VA occurrence and the factors of anterior MI,chest pain time?24 hours,lesion of proximal and mid-LAD,and age>60.Except age>60,they are all statistically proved as strongly correlative factors.Conclusion: First,the VA occurrence is correlated with factors such as age,anterior MI,?4 ST segmentation elevation,chest pain time?24 hours,smoking,and lesion of proximal and mid-LAD.Second,according to the multi-factor logistic regression analysis,there are positive correlations between the VA occurrence and factors of anterior MI,chest pain time?24 hours,lesion of proximal and mid-LAD and age>60,with the first three factors significantly correlated with the occurrence of post-MI LVA.Lastly,there is no evidence for the direct correlation between LVA and other factors such as gender,high blood pressure,diabetes,hyperlipidemia,hyperuricemia,angina pectoris history,MI history,single/double/multi-vessel diseases or occlusions of the invaded vessels.