The Relationship Between Sleep Structure And Prognosis In Childhood Rolandic Epilepsy

Objective:A retrospective analysis of the whole nature sleep in 30 children with Rolandic epilepsy(RE)was performed to demonstrate the sleep strctrue changes and its relationship with prognosis.Methods:From January 2016 to November 2017,30 children with RE who were diagnosed as RE at the Bethune First Hospital of Jilin University were selected as the case group.20 normal children with gender-agematched were selected as the control group.A 15-hour video EEG(15hVEEG)monitoring including the whole night natural sleep period were performed in two groups,according to the rules,terminology,and technical specifications of the American Academy of Sleep Medicine Manual for the Scoring of Sleep and Associated Events,analyze the sleep structure changes during sleep period of two group children frame by frame in 30-second frames,and the condition and efficacy of the children were followed up to identify the relationship between sleep structure changes and prognosis in children with RE..Results:Compared with the control group,the proportions of NREMI and NREMII stages to total sleep time in children with RE were significantly longer.The NREMI period was prolonged.The proportion of REM wasdecreased and the REM period was shortened in RE children(P<0.5).The number of arousal in the poor-prognosis group was higher than that in the good-prognosis group.The NREM III period in the poor-prognosis group was significantly shorter than that in the good-prognosis group(P<0.05).Conclusion:1.There were obvious sleep structure changes in children with RE,with increased proportion of NREMI and NREMII to total sleep time,prolonged time of NREMI period,decreased proportion of REM to total sleep time,and shortened REM period.2.Increasing of arousal frequency and shortening of NREM III period possibly are clues of poor prognosis in RE children.