Related Factors Of Clinical Efficacy Of Microvascular Decompression For Primary Trigeminal Neuralgia

Objective:To investigate the influencing factors of clinical efficacy of microvascular decompression in patients with primary trigeminal neuralgia,and analyze the results to guide treatment in return.Method:At first,analyzing the clinical data of 80 patients with primary trigeminal neuralgia who were treated with microvascular decompression in the Department of Neurosurgery at the First Affiliated Hospital of Guangxi Medical University from September 2013 to September 2017 retrospectively.Then took a detailed analysis of the patient's preoperative clinical symptoms,intraoperative findings,and postoperative follow-up clinical efficacy results.Moreover,nine factors,including gender,age,ipsilateral,range of pain,course of disease,clinical type,intraoperative responsible blood vessels,degree of oppression,and degree of decompression,were tested by the single factor X2 test method.Last but not least,analyzed those meaningful indicators examined by univariate X2 test with Logistic multivariate regression analysis to evaluate independent risk factors affecting the clinical efficacy of MVD in the treatment of PTN.Results: the result of analyzing the effect of those nine factors including gender,age,ipsilateral,range of pain,course of disease,clinical type,intraoperative responsible blood vessels,degree of oppression,and degree of decompression via univariate Logistic analysis shows that: No statistical difference is found between age,gender,ipsilateral,course of disease and clinical efficacy(P>0.05).While there is statistically difference between the extent of pain,clinical types,responsible blood vessels,degree of compression,degree of decompression,and clinical efficacy(P < 0.05).Multivariate logistic regression analysis shows that there is statistical difference among liability vessels,degree of compression,degree of decompression and clinical efficacy(P<0.05),which indicates these three are risk factors affecting the clinical efficacy of MVD after PTN.Conclusion: The patient's gender,age,ipsilateral,and disease course have no effects on clinical efficacy.However,the intraoperative responsibility blood vessels,compression of the single root artery,lighter nerve compression,and adequate decompression of the nerve during the operation are closely related to the therapeutic effect.