To Evaluate The Osteogenic Effect Of Ostebone In The Repair Of Jaw Defects By Gray Ratio

Objective The mandible is a very important bone tissue structure in the maxillo-facial region,which plays an irreplaceable role in mastication,language functionand appearance.But mandibular defect is aslo a common and frequently encountered disease in clinical practice.It can be caused by many factors.For example,the invalid cavity after jaw cyst surgery is one of the reasons of bone defect.Therefore,the rehabilitation and reconstruction of bone defect has always been a focus of clinical research.CBCT can display very clear and accurate images for highly mineralized tissues,which has become the preferred examination for bone defect-based diseases.Osteobone is a new type of inorganic ceramic scaffold material.To evaluate the osteogenesis of Osteobone implanted into jaw defects by imaging gray ratio changes.Methods 20 patients with mandibular bone defects caused by odontogenic cysts were selected,including 13 males and 7 females,aged 20-55 years.The range of bone defects in all patients was larger than 2 cm × 2 cm × 2 cm.Osteobone were implanted,and CBCT was taken before preoperative and 1,3,6 months after surgery,the average gray values of affected side to sagittal plane,coronal plane measured by the software of the fixed point and section.Than,the gray ratio of affected side to sagittal plane,coronal plane and healthy side was calculated.Spanova and t-test results were statistically analyzed.Results 1.No matter sagittal or coronal plane,there was a significant difference in the average gray value between the bone graft side and the healthy side at different time points before and after operation(P > 0.05).2.The gray scale ratio of the affected area and the healthy side was the lowest before operation,and increased to the maximum at the first month after operation;the third month after operation was significantly lower than that in the first month after operation;the gray scale ratio of 6 months after the operation and the healthy side was close to 1.Conclusion Osteobone has a good osteogenic effect in the repair of bone defects in the mandibular posterior region.Grayscale ratio can directly show the difference of bone mineral density in affected and normal areas before and after operation,which can be regarded as an objective evaluation basis for observing osteogenic effect.