Logistic Regression Analysis Of Risk Factors For Surgical Site Infection After Spinal Surgery And Preliminary Study On Its Treatment

Objective To study and analyze the risk factors of postoperative spinal infection and pathogenic bacteria,to explore their treatment methods and epidemiological characteristics,to provide theoretical support for surgeons in clinical work,so as to achieve the purpose of reducing the postoperative infection rate of the spine.Methods This study used a retrospective analysis of patients undergoing spinal surgery at the Department of Spinal Surgery,First Affiliated Hospital of Guangxi Medical University from January 2017 to December 2017.The main observations were preoperative factors(gender,age,diabetes,hypertension,smoking,history of previous spinal surgery,body mass index,muscle strength,preoperative ASA score,Preoperative diagnosis),intraoperative factors(Surgicalmethods,blood loss,blood transfusion,operation time,internal fixation,bone grafting,surgical responsibility segment,cerebrospinal fluid leakage),postoperative factors(drainage tube indwelling time,transfer to ICU,postoperative human serum albumin).The t-test was used for the comparison between the measurement data sets;the ?2 test was used for comparison between the count data sets.Factors that are significant for univariate analysis are determined by multivariate logistic regression analysis to determine the independent risk factors for postoperative infection in the spine.Results This study found that from January 2017 to December 2017,there were 37 surgical site infections in our department after spinal surgery,and the infection rate was 5.8%(37/642).Among them,Age,body mass index,surgical responsibility segment,bone grafting,blood transfusion,operation time,preoperative diagnosis,and surgical methods were risk factors for surgical site infection after spinal surgery.Multivariate logistic regression revealed that age,body mass index,bone grafting,preoperative diagnosis,surgical methods,and blood transfusion were the main risk factors for surgical site infection after spinal surgery.Conclusions 1.Univariate analysis showed that age,body mass index,surgically-responsive segment,bone grafting,blood transfusion,operation time,preoperative diagnosis,and surgical approach were risk factors for surgical site infection after spinal surgery.Among them,age,body mass index,bone grafting,preoperative diagnosis,surgical method,and blood transfusion were the mainrisk factors for surgical site infection after spinal surgery.2.In the case of age,surgical responsibility segment,preoperative diagnosis classification can not be changed,preoperative weight loss,shortening the operation time,reducing intraoperative or postoperative blood transfusion,minimally invasive surgery,etc.can effectively prevent the occurrence of postoperative infection.3.The main pathogen of surgical site infection after spinal surgery in our department is gram-negative bacteria,mainly Escherichia coli(38.5%)?...