Relation Between Plasma D-Dimer Levels And Degree Of Coronary Artery Leisions In Acute Myocardial Infarction

Objective:To observe the relationship between plasma D-Dimer levels and degree of coronary artery leisions in acute myocardial infarction.Methods:Choose the date of 210 patients from August 2015 to April 2017 in the First Affiliated Hospital of Medical University of Anhui.Patients were divided in two groups,one is AMI group(n=110),another is non-AMI group(n=100).The differences of plasma D-dimer between the two groups were observed by measuring D-dimer levels.According to the results of coronary angiography,observe the correlation between the two groups in plasma D-dimer.Then AMI group were divided into single vessel lesion group,double vessel lesion group and triple vessel lesion group.Compared with the level of plasma D-dimer in the three subgroups and non-AMI group.At the same time,the correlation between the level of d-dimer and the severity of coronary artery disease was observed by calculating the Gensini score of each patient in the AMI group.Results:(1)Plasma D-Dimer levels were higher in AMI group(0.77±0.34)mg/L than those in non-AMI group(0.30±0.14)mg/L(P<0.05).(2)Plasma D-Dimer levels were different among the four subgroups(P<0.05).(3)The level of plasma D-Dimer and Gensini score are positively correlate in AMI group(r=0.516,P<0.05).Conclusion:Plasma D-Dimer levels were higher in patients with acute myocardial infarction than those without AMI;the levels of plasma D-Dimer may reflect the degree of coronary artery stenosis in AMI.