The Value Of Radiofrequency Coagulation Device In Resection Of Large Hepatocellular Carcinoma

BackgroundPrimary liver cancer is a common malignancy of the digestive system and seriously threatens people's lives and health.Although China has made considerable progress in the prevention,screening,diagnosis,and treatment of liver cancer in the past decade or so,the incidence and mortality have risen.The specific etiology and mechanism of hepatocellular carcinoma is still unknown.The early onset symptoms are often not typical.Liver transplantation is the only curative surgical procedure.Because of the high cost,lack of liver resources,and the need for long-term use of immunosuppressive drugs after surgery,This treatment is difficult to spread.Surgical resection is an important and effective treatment for liver cancer.As long as R0 resection is ensured,it can effectively improve the patient's 5-year survival rate.It can be used as an alternative therapy for liver transplantation.However,the surgical procedure has a large amount of blood loss and high risk for surgeons.It has always been a huge challenge,especially for large liver cancer or huge liver cancer.Radiofrequency coagulation device is an auxiliary apparatus for liver resection using the principle of RFA.It is equipped with 4 bipolar electrodes(4X electrodes)with cooling system.It converts electromagnetic energy into heat during operation,and the tissue around 4X electrode undergoes coagulative necrosis due to high temperature.A coagulation necrosis zone with a width of 1 cm is formed,and the tissue is removed and separated along the middle part of the necrotic zone during surgery.This is a newly emerging surgical method for assisted liver cancer resection.Objective Evaluation of the value of radiofrequency coagulation device in surgical resection of large hepatocellular carcinomaMethods Using the method of retrospective study,from August 2015 to August 2017 in the Department of hepatobiliary surgery of the First Affiliated Hospital of Zhengzhou University underwent Clamping large liver resection in 42 patients(control group)during the same period,resection of radiofrequency coagulation device assisted large hepatocellular carcinoma in 34 patients(observation group).The basic data of the two groups were compared and analyzed.Routine preoperative preparation was performed.Operation time,intraoperative blood loss,first hepatic portal blocking rate and intraoperative blood transfusion rate were statistically analyzed in two groups.SPSS 22 software was used to process related data in this study.Results1.The operation time of the observation group was 166.9±21.7 min,and the operation time of the control group was 209.5±23.0 min.The difference was statistically significant(P<0.05).2.The intraoperative blood loss in the observation group was 380.9±81.3ml,and the intraoperative blood loss in the control group was 685.2±161.6ml,and the difference was statistically significant(P<0.05).3.The blocking rate of the first porta hepatis was 0.206(7/34)in the observation group and 0.714(30/42)in the control group,the difference was statistically significant(P<0.05).4.Intraoperative blood transfusion rate was 0.147(5/34)in the observation group and 0.357(15/42)in the control group.The difference was statistically significant(P<0.05).Conclusions Radiofrequency coagulation device assisted surgical resection of large hepatocellular carcinoma is safe and efficient.It can significantly shorten the operation time,reduce the intraoperative risk,and is beneficial to postoperative recovery.