Consistency Of Screening Tools For Diabetic Peripheral Neuropathy

Objectives: The incidence of diabetic peripheral neuropathy(DPN)in type 2 diabetes mellitus(T2DM)was screened using Michigan Neuropathy Screening Instrument(MNSI),Diabetic Neuropathy Symptom score(DPN),128 Hz Tuning Fork,and 10 g monofilament test.Various screening tools were used to diagnose DPN in the differences,correlation and consistency.Methods: MNSI,DNS,128 Hz tuning fork,10 g monofilament test were used to screen for DPN included 130 patients with T2 DM who were admintted to the outpatient department and inpatient department of Affiliated Hospital of North Sichuan Medical College.Spearman rank correlation analysis was used to assess the correlation between the scores and Kappa analysis was used to assess its consistency in the diagnosis of DPN.Results: The study eventually included 130 patients with T2 DM,78males(60%)and 52 female(40%),aged 54 ± 11 years,duration of diabetes 5(2-10)years.1.The incidence of screening methods using MNSI,DNS,128 Hz tuning fork,10 g monofilament test was 51%,43%,45% and 27%,respectively.2.Several screening methods were positively correlated with each other(in total,P <0.05).Among them,the questionnaire score of the MNSI(MNSI-Q)was highly correlated with DNS(Spearman r = 0.754;P <0.05),and the physical assessment score of the MNSI(MNSI-P)was significantly correlated with 128 Hz tuning fork(Spearman r = 0.58,P <0.05).Theremaining screening methods are less relevant to each other(P < 0.05).3.There are different degrees of consistency among several simple screening methods(in total,P <0.05).MNSI-Q combined MNSI-P with MNSI-P had the highest consistency(?=0.908,P <0.001).MNSI-Q combined MNSI-P with 128 Hz tuning fork,MNSI-P with 128 Hz tuning fork,MNSI-Q with DNS was better consistency(a ?appa value of 0.524,0.582,0.497,respectively),while the consistency of other screening methods was poor(in total,P <0.05).Conclusion:1.At present,several commonly screening methods were used in clinical diagnosis of DPN prevalence differences exist.There is a positive correlation between each other.2.The diagnostic consistency is unlike.The consistency of MNSI and DNS is as good as MNSI and 128 Hz tuning fork.