| Brucellosis is a bacterial infectious disease caused by Brucella.It is the second kind of zoonotic disease in China.The main purpose of this study is to investigate the current situation of large-scale meat goat farming and the prevalence of brucellosis in some areas of Anhui Province,in order to provide a basis for scientific,effective prevention and control of brucellosis in Anhui Province.In this study,17 large-scale meat goat farms in 6cities and 8 counties(districts)divided into Anhui administrative region were investigated by questionnaire,and the current breeding situation of the 17 large-scale farms was preliminarily made.it mainly includes whether to buy,previous epidemic history and sanitary disinfection and so on.1291 serum samples were collected from 11 large-scale meat goat farms for serological screening of brucellosis infection.Three commercial tiger red antigen reagents were used to detect 150 sera with known infection,and highly sensitive tiger red reagents were screened for primary screening of brucellosis.The collected serum samples were serologically detected by tiger red plate agglutination test(RBPT)and competitive enzyme-linked immunosorbent assay(c ELISA).The results showed that 44 of the 1291 samples collected in this survey were positive,and the overall positive rate was 3.41%.The serum samples from 2 of the 11 large-scale meat goat farms had brucellosis positive,and the population positive rate was 18.18%.The positive rates of the two positive farms were 4.08% and 9.85%,respectively,indicating that the prevalence of brucellosis was quite different in some large-scale farms in Anhui.And the infection in some large-scale farms is more serious.Statistical analysis of epidemic prevention and control measures in large-scale farms in some areas of Anhui Province shows that the farm mainly uses vaccination to prevent and control the disease,and the farm goats with self-breeding combined with captivity have good physique and less diseases in the herd.There is a certain degree of immunity to brucellosis infection. |