Research On Drug Transportation Mechanism Based On Molecular Communication

Molecular communication is closely related to nanotechnology,biotechnology and communication technology.With the continuous development of emerging technologies,molecular communication technology combines innovation in a variety of subject areas.Molecular communication system is expected to achieve new revolutionary applications,such as the sensing of target substances in biotechnology,intelligent drug delivery in medicine and monitoring of oil pipelines or chemical reactors in industrial environment.At present,molecular communication is still in the stage of theoretical research,and there are a few simulation platforms,but the experimental verification is not comprehensive enough.This thesis mainly studies the mechanism of drug transport based on molecular communication.The entire communication process is that the drug is released from the sending end to the cell fluid,and the drug molecules as information molecules are transmitted to the target cells through the medium,which is the receptor ligand binding mechanism.Information molecules bind to receptors on the cell surface,enter the cell through receptormediated ion channels,and eventually act on the DNA or protease in the cell.The entire communication process is based on the diffusion movement of molecules.However,with the free diffusion of information molecules in the fluid medium,the number of information molecules received at the receiving end will decrease significantly with the increase of the transmission distance,so the communication range of the diffusion molecule communication is limited.Inspired by the traditional wireless communication relay,this thesis uses a transceiver as a relay in diffuse molecular communication,and then expands the communication range to become a reliable solution.Therefore,in this thesis,a repeater is added to the research drug transport system.The repeater can allow more drug molecules to act on the cells to be treated,can control the elimination rate of the drug,and can improve the drug treatment effect.This thesis explores inter-symbol interference and channel noise in the system model,and then establishes a system model,that is,a common binary channel system.This system is used to analyze the channel transmission capacity and derive the maximum transmission rate.The density shift keying modulation is used to obtain the optimal position of the repeater with the smallest bit error rate.In the end,the effect of the repeater was verified by biological cell scanning experiments.The mechanical characteristics of the cell morphology obtained from the scanning were used to reflect the results of different concentrations of drugs on cells.The experimental results obtained in this paper have important theoretical value and guiding significance for future experimental verification research of molecular communication.