Preparation And Properties Of Graphene-based Composite Antibacterial Materials

At present,the abuse of antibiotics is a global challenge.Silver has been widely used as antibacterial agent since ancient times.Due to size effect,silver nanoparticles have more excellent antibacterial activity.However,the long-term use and contact of silver nanoparticles will cause toxicity to some organs,and the antibacterial activity of silver nanoparticles is often affected by oxidation deactivation and agglomeration.Therefore,it is necessary to find a new method or a new material to solve these problems of drug resistance,which can reduce the amount of silver nanoparticles,improve the dispersion of silver nanoparticles in the system,and have good antibacterial activity.Graphene is a two-dimensional nano-material with honeycomb crystal structure,which is formed by single-layer carbon atoms through sp~2 hybridization.Because of its unique structure,graphene has rich and excellent physical and chemical properties.Graphene has large specific surface area,rich in active functional groups,and antibacterial activity.It can not only be used as a nano building module for preparing new composite materials,but also be used to disperse and anchor expensive materials Metal and other nanoparticles.It can be widely used in drug delivery,biosensor,photodynamic cancer treatment and so on.Based on the above research background,this paper mainly focuses on the preparation of graphene-based compounds and these antibacterial activities.The structure and morphology of the film samples were characterized by X-ray powder diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),Fourier transform infrared spectrometer(FT-IR),X-ray electron spectroscopy(XPS)and so on.The hydrophilicity/hydrophobicity and antibacterial properties of the samples were measured by the wetting angle meter and the bacteriostatic ring method.The main research contents are as follows:1.In this paper,a modified Hummers method was used to prepare graphene oxide.This method takes a short time,is easy to operate and has a good degree of oxidation,and has rich oxygen-containing functional groups on the edges.In the drying of the drip film,the film formation performance is good,and it can be formed on any flat substrate;2.Using glucose solution as reducing agent,Ag/GO colloid was obtained by hydrothermal reaction of silver ammonia solution and graphene oxide;using step heat treatment method,coating material based on reduced graphene oxide(rGO)was obtained on the substrate,so that the composite film has a good antibacterial ability against Gram-negative bacteria and Gram-positive bacteria and the reduction Antibacterial activity of the composite film before and after.3.Triangular silver nanoparticles were synthesized by a simple and easy-to-use light-induction method.Triangular silver nanoparticles with good microscopic morphology,dispersion,and stability were prepared by adjusting the synthetic conditions such as light time,reactant ratio,and pH value.Through real-time monitoring of its growth process,the growth mechanism of triangular silver nanoparticles prepared by light-induced method was explored.4.Triangular silver nanoparticles of different sizes prepared by the photo-induction method were modified on a graphene oxide substrate with a simple room-temperature stirring method without adding any toxic coupling agent and dispersant to prepare antibacterial activity.Trace triangular silver nanoparticles/graphene oxide composite film.The relationship between the size of the loaded triangular silver nanoparticles and the antibacterial activity was explored.