Electrochemical Detection Of Phenols Based On Boron Nitride Sensing

Phenol compounds from medical,chemical industry and machinery production can be continuously hazardous to our health,water and soil environment.Paracetamol?PCM?is one of the most widely employed drug in healthcare to cure fever and pain,and its main hydrolytic product is 4-aminophenol?4-AP?.The abuse of PCM and 4-AP can lead to public health issues and serious risks of illness.Therefore,it is necessary to develop a simple,efficient and sensitive sensing platform for the determination of phenol compounds.The sensors fabricated with boron nitride?BN?combined with ionic liquids?IL?,tungsten disulfide?WS₂?or gold nanoparticle?Au NPs?materials were used to detect PCM and 4-AP.The obvious performance for detection process was shown under the best conditions due to the synergetic effect and high catalytic oxidation activity.Moreover,these new electrochemical sensors become as an excellent candidate platform to detect phenols in real samples.The main research contents are as follows:1.An electrode modified with a nanocomposite of boron nitride,ionic liquid and tungsten disulfide for 4-AP detectionBN was prepared by a“solvent cutting”method,and the IL and WS₂ nanocomposite were anchored on the BN by an ultrasonic method.A ternary 4-AP electrochemical sensor was modified with boron nitride,ionic liquid and tungsten disulfide nanoparticles.BN and its hybrids were examined by X-ray diffraction,Raman spectrum,scanning electron microscopy?SEM?,energy dispersive spectrometer and transmission electron microscopy.When the BN-IL-WS₂ composites were coated on the glassy carbon electrode,the detection performance of4-AP was greatly amplified due to the strong synergetic catalytic effect.The voltammetric behavior on the BN-IL-WS₂/GCE?with working potential of 0.29V vs.Ag/Ag Cl?in 4-AP solution with a p H of 6.0 is linear in the 0.01-50??4-AP concentration range,and the detection limit is 3 n M.The modified electrode exhibited high stability and selectivity and can be applied for the determination of 4-AP in seawater and dispersions of pharmaceutical.The results were consistent with those procured by HPLC.2.An electrodeposited gold nanoparticle/boron nitride composite for electrochemical sensing detection of PCMA simple and eco-friend electrochemical sensor for PCM detection was developed using the boron nitride and Au nanoparticles composite.The Au NPs were deposited onto the prepared BN/GCE by an electrochemical method.The electrochemical properties of PCM in a three-electrode system was characterized by differential pulse voltammetry and cyclic voltammetry.Moreover,SEM reveals the morphology of the BN-Au/GCE.The synergic effect between Au NPs and BN nanomaterial enhanced the sensitivity and catalytic performance of PCM detection.It can promote the electron transfer process between the electrolyte and the surface of the glassy carbon electrode.The current signal have a significant enhancement at p H=8.0?0.1 mol/L PB?.A wide linear range of 0.01-50?M was obtained by DPV with a LOD of 7.8 n M.The proposed sensor was applied to rapidly and sensitively detect PCM from tap water.For the spiking test,the recoveries of PCM is 99.6%-101.2%.This research provides a new way for the development of BN-based composites with selective and sensitive detection of PCM and it is also desirable for environmental monitoring.