Study On Syntheses,Properties And Applications Of Salamo-based Photochemical Sensors

In recent years,the problems caused by industrial production have become more and more serious.Heavy metal ions pollution and highly toxic anions pollution have brought serious environmental problems to human society.Therefore,chemosensors have been widely studied and received more and more attentions in the fields of environment and biology.In this thesis,the synthesis and characterizations of several Salamo-based chemosensors are mainly studied,and the sensor molecules are applied to the identification and labeling of related ions in water samples and biology.At the same time,the identification mechanisms are analyzed by means of nuclear magnetic,mass spectrometry and so on.The main content is divided into the following parts:1.The significance of the fluorescence chemosensor on the recognition field,the structure of the chemosensor,the recognition mechanism and its application are briefly introduced.The identification,detection and development in recent years of several anions and cations involved in this thesis are analyzed.2.Two Salamo-based chemosensors H₂L¹ and HL² and their copper（II）complexes L¹-Cu²⁺and L²-Cu²⁺are designed and synthesized.More than ten kinds of anions such as F^-,Br^-,I^-,Cl^-,H₂PO₄^-,CN^-,CH₃COO^-,HPO₄^2-,HS^-,CO₃^2-,S^2-,NO₃^-,HCO₃^-,P₂O₇^4-and NO₂^-are added in L¹-Cu²⁺and L²-Cu²⁺,they show specific recognition for CN^-ions,and the two sensor molecules could recognized CN^-ions by naked eyes in sunlight.The sensor L¹-Cu²⁺shows a strong absorption peak at 498 nm,and the sensor L²-Cu²⁺shows a strong absorption peak at 500 nm.The detection limits are as low as 4.56×10^-7 M and 2.40×10^-7 M,respectively.Through research methods such as high-resolution mass spectrometry and controlled experiments,the appropriate coordination mechanism is inferred.Beyond that,the two chemical sensors are also applied to CN^-detection in several water samples in real life.3.A new sensor molecule H₂L³ is designed and synthesized,which is characterized by nuclear magnetic,mass spectrometry and fluorescence spectroscopy.H₂L³ could recognize Al³⁺ions well in the fluorescence spectra.The limit of detection is as low as 5.98×10^-9 M.Under the irradiation of 365 nm ultraviolet wavelength,the solution shows a bright green change.It is worth noting that the sensor molecule has less cytotoxicity,so the sensor molecule can be used as a tool for exogenous detection of Al³⁺ions in vivo at low concentrations.As the first Salamo-based fluorescent chemosensor realizing exogenous biological imaging in zebrafish,its success expands the application of Salamo-based fluorescent sensor in the field of biology.4.The sensor molecule H₂L⁴ and its copper（II）complex L⁴-Cu²⁺are synthesized using2-hydroxy-3-methoxybenzaldehyde,1,2-diamineoxyethaneand2-hydroxy-5-nitrobenzaldehyde as raw materials.L⁴-Cu²⁺can realize specific two-channel recognition for S2-ions in ultraviolet-visible absorption spectrum and fluorescence spectrum experiments,and can realize naked-eye recognition under sunlight.Through research methods such as mass spectrometry,the binding mechanism is analyzed,and it is speculated that the dual-channel recognition for S^2-ions is due to the binding of Cu²⁺ions in the sensor molecule,thus achieving specific recognition.In order to further broaden the application of Salamo-based compounds in ion detection,this chemosensor molecule is used to detect H2S gas and gained satisfactory results.