Preparation And Performance Investigation Of Polymer Hydrogel Sensor

Under the background that the number of targets is gradually diversified and the detection environment is increasingly complex,the design and synthesis of macromolecule hydrogel fluorescent probe sensor is a valuable research direction in the field of fluorescent probe application.In this paper,a small molecule fluorescent probe with high sensitivity and specific selectivity was designed and synthesized,and its sensing performance and recognition mechanism were studied.Then the synthesis of small molecular fluorescent probe with hydrogel monomer free radical copolymerization,and the preparation of the supramolecular hydrogel with small molecular fluorescent probe for host-guest interaction were low optical background,recognition performance of macro supramolecular hydrogel fluorescent probe sensor,and study examines the macro supramolecular hydrogel polymer fluorescent probe sensor performance and the recognition performance.The main research contents and conclusions are listed as follows:1. Fluorescein derivative fluorescent probe FLA was prepared with fluorescein as the fluorescence group and its structure characterization and optical performance were tested.Choose acrylamide,hydroxyl ethyl methacrylate,methyl methacrylate as the monomer,N,N'-methylene double acrylamide as crosslinking agent,the initiator of ammonium persulfate and catalyst N,N,N',N'-tetramethyl ethylenediamine and under the action of the FLA copolymerization preparation of supramolecular hydrogel sensors,research of hydrogel sensor recognition properties,swelling properties and reversibility.2. Rhodamine 6G derivative fluorescent probe R6GLA was prepared with rhodamine 6G as the fluorescence group and its structure characterization and optical performance were tested.Start with acrylamide and methyl methacrylate as monomer,N,N'-methylene double acrylamide as crosslinking agent,the initiator of ammonium persulfate and catalyst N,N,N',N'-tetramethyl ethylenediamine and R6GLA copolymerization under the action of the preparation of hydrogels sensors,examine recognition performance and reversible hydrogels sensor and the sensor of water gel,on the basis of combining it with poly(N-isopropyl acrylamide composite double hydrogel sensors,to study the preparation of double water gel sensor performance and win min deformation behavior.3.Rhodamine 6G derivative fluorescent probe R6GS was prepared with rhodamine6G as the fluorescence group and its structure characterization and optical performance were tested.Using acrylamide and methyl methacrylate as copolymer,N,N'-methylene diacrylamide as crosslinking agent,the hydrogel sensor was prepared by copolymerization with R6GS under the action of initiator ammonium persulfate and catalyst N,N,N',N'-tetramethylethylenediamine.With acrylamide and beta cyclodextrin as monomer,N,N'-methylene double acrylamide as crosslinking agent,the initiator of ammonium persulfate and catalyst N,N,N',N'-tetramethyl ethylenediamine copolymerization under the action of supramolecular hydrogel carrier preparation,the preparation of the supramolecular hydrogel carrier in DMSO R6GS soaking,in the form of host-guest interaction sensor in water gel preparation and the recognition performance and reversibility.4.The fluorescein derivative fluorescent probe FLA-Boe was prepared by using fluorescein as the fluorescence group and phenylborate as the specific recognition group,and its structure characterization and optical properties were tested.Acrylamide and n-cyclodextrin were selected as copolymer monomers and N,N'-methylene diacrylamide was used as cross-linking agent to prepare supramolecular hydrogel carrier by copolymerization under the action of initiator ammonium persulfate and catalyst N,N,N',N'-tetramethylethylenediamine.The prepared supramolecular hydrogel carrier was immersed in FLA-Boe DMSO solution,and the hydrogel sensor was prepared in the form of master-guest interaction and its recognition performance was studied.Research significance of this paper:1.The design and synthesis of four small molecular fluorescent probe and to fluorescent probe of the preparation of the synthesis of a series of macro supramolecular hydrogel with recognition sensor,explore small molecules will be in the form of free radical copolymerization functional polymer preparation supramolecular fluorescence probe synthesis scheme of hydrogel sensor,and the use of the preparation of macro supramolecular hydrogels by host-guest interaction and fluorescent probe molecules made functional polymer materials and then assembled into supramolecular hydrogel sensor preparation route.2.The exploration on the basis of retain the recognition performance,preparation of Hg²⁺response sensor type water gel and poly(N-isopropyl acrylamide hydrogel double composite hydrogel,get both Hg²⁺recognition performance with temperature sensitive macroscopic deformation properties of the composite hydrogel sensor,will identify performance and deformation behavior into a hydrogel sensor system.Based on the functional independence of the hydrogel sensor,the potential of supramolecular hydrogel sensor to be a functional module of supramolecular hydrogel and to combine supramolecular hydrogel components with other properties can be demonstrated.3. Through the preparation of supramolecular hydrogel sensor for solving small molecular fluorescent probe in the field of fluid monitoring measurement and the accumulative detection is difficult to cast the problem,extending the application of fluorescent probes on the usability,sensor and water gel preparation process is simple,without any pretreatment when using,can further reduce the complexity of the fluorescent probe when using,expand the scope of application of fluorescent probe.