| In recent years,with the rapid development of organic synthesis methodology,the application range of organic compounds has also expanded.In the field of asymmetric catalysis,chiral oxazoline derivatives could catalyze many asymmetric reactions as a simple and easily modified catalyst;In the application of fluorescent materials,phenanthroline and its derivatives have great potential for application due to their good planar structure and good metal coordination ability.Triazole derivatives are also used in many fields due to their stable structure and good metal coordination ability,but they are still in the initial stage.Therefore,the paper design the introduction of triazole groups into chiral oxazolines and phenanthroline derivatives and their properties have been explored.The following innovations have been obtained:Firstly,five phenanthroline derivatives were synthesized by the method of TA-Au catalyst phenylacetylene,8-aminoquinoline and aromatic aldehyde.It not only expands the application range of TA-Au catalyst,but also provides a new method for the synthesis of phenanthroline derivatives.At the same time,through screening,it was found that C2 had a remarkable fluorescence selectivity to silver ions with a fast response（<20 s）and a minimum detection limit of 2.39×10-99 mol/L,which provided a new research idea for the development of new silver ion probes.Secondly,three chiral 2,5-dioxazoline-1,2,3-triazole derivatives and N2-oxazoline-substituted-1,2,3-triazole derivative were synthesized using chiral L-aminol as chiral source.These triazole-oxazoline derivatives were used as asymmetric catalytic ligands to catalyze Henry reaction of p-nitrobenzaldehyde with nitromethane.The reaction conditions were optimized and 95%yield and 20%ee value were obtained.It not only extends the types of chiral oxazoline ligands,but also provides some references for the design and synthesis of chiral ligands containing 1,2,3-triazole structure. |
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