Visible-Light-Promoted Organic Reactions Involving Disulfides

Sulfur-containing compounds play an irreplaceable role in our daily lives.Whether it is a natural product or a C-S bond in an organism,it can be detected.In the era of continuous innovation,researchers have been devoted to exploring the construction method of C-S bond,and its generation method has also been explored on a large scale.Among them,the method promoted by visible light is in a hot position.This is due to the advantages of simple preparation,low cost,convenient use and low pollution of photocatalyst.The core of this article is to promote the reaction of disulfide with cinnamic acid and 1,6-enynes under the action of visible light,as follows:1.Under the visible light irradiation,the decarboxylation coupling reaction of disulfide and cinnamic acid is realized.For the synthesis of vinyl sulfone compounds,this reaction provides a novel way to replace existing synthetic methods.Here,we use disulfides as sulfonylation reagents.The reaction conditions of this strategy are simple and clear,the operation is not complicated,it is relatively environmentally friendly,and the substrate has a broad spectrum.2.In this strategy,1,6-enyne and disulfide are used as reactants,acridine salt is used as a photocatalyst,and N-Methyl-Pyrrolidone is used as a solvent to obtain phenylthiobenzofuran compounds at room temperature.This reaction realizes the oxidative cyclization series reaction of 1,6-enyne and disulfide under visible light irradiation and no transition metal conditions.The reaction has the characteristics of simple operation,good yield,less harsh reaction environment and green environmental protection.