The Preparation Of Bi₂WO₆ Micro-nanostructured Materials And The Study On Removal Of Antibiotics In Water

Quinolones are widely used in humans and livestock because of their broad spectrum of antibacterial activity.At the same time,antibiotics enter the natural environment through a variety of different pathways,but the substance is difficult to degrade naturally,so residual antibiotics pose a potential threat to the health of the ecosystem and humans.Therefore,it is of great significance to establish a highly efficient detection and treatment process of quinolone antibiotics.In recent years,the photocatalytic oxidative degradation of organic wastewater by Bi₂WO₆ photocatalyst has been reported,showing excellent photocatalytic activity of this material.This paper adopts SPE-UPLC-MS/MS for simultaneous detection and analysis of Marbofloxacin?MAR?,Enrofloxacin?ENR?,Dsnfloxacin mesylate?DAM?,Difloxacin?DFLX?,Ofloxacin?OFL?,Lomefloxacin hydrochloride?LOM?,Ciprofloxacin hydrochloride?CIP?and Norfloxacin?NOR?.Bi₂WO₆ photocatalyst with good photocatalytic activity was prepared by hydrothermal method,and a simultaneous photocatalytic oxidation degradation of eight quinolone antibiotics was developed,to reduce the pollution of quinolone antibiotics in water.8 quinolone antibiotics in environmental water samples were enriched and extracted by solid phase extraction.The solid phase extraction conditions were optimized,and a pretreatment method for enriching 8 quinolone antibiotics in various water bodies was established.The solid phase extraction membrane was activated by methanol,acetone-methanol solution and ultrapure water.The methanol and methanol-acetone?V:V,1:1?solution was used as the elution solvent,and the HLB solid phase extraction membrane was used to treat the environmental water samples.Through this method,the spiked recovery rate of various target antibiotics was 77%¹02%.It meets the need for trace antibiotic residue detection in environmental water samples.The UPLC-MS/MS method was used to simultaneously detect the residues of 8quinolone antibiotics in water.UPLC-MS/MS technology has a wide detection range,high sensitivity,excellent resolution and strong anti-interference ability,suitable for the detection of antibiotics in various sample substrates.After optimization of the conditions,the detection limits of the 8 target antibiotics were 0.04⁰.69?g/L?S/N=3?,and the correlation regression coefficient R² reached 0.999.In this way,the quinolone antibiotic residues in the actual water samples?pharmaceutical enterprises and surface water?were tested and analyzed.The results showed that there were a large amount of norfloxacin and ofloxacin in the pharmaceutical wastewater,and the concentration reached 755.26¹809.14ng/L;the concentration of quinolone antibiotics in surface water ranges from 21.89ng/L to 70.51ng/L.Bi₂WO₆ photocatalyst with good photocatalytic activity was synthesized by hydrothermal method.By optimizing the preparation process,the optimal preparation method of Bi₂WO₆ photocatalyst was as follows:1mmol Bi?NO₃?₃·5H₂O,0.5mmol Na₂WO₄·2H₂O,citric acid concentration was 0.05mol/L,NaHCO₃ addition is 0.05mol/L,hydrothermal reaction temperature was 190°C,the hydrothermal reaction time was 18h and the sample drying temperature was 60°C.The structure and chemical properties of Bi₂WO₆ photocatalyst were characterized by SEM,TEM,XRD,EDS,UV-vis,BET and PL.The results show that the prepared Bi₂WO₆ photocatalyst has good crystallinity and a specific surface area of35.40m²/g.And this catalyst shows good photocatalytic activity against antibiotics.Photocatalytic oxidation degradation of 8 quinolone antibiotics by Bi₂WO₆ photocatalyst prepared by hydrothermal method.By optimizing the photocatalytic oxidation experimental conditions,it was found that the 8 quinolone antibiotics have an ideal removal efficiency.The removal rate of 8 antibiotics were MAR:97.46%,ENR:99.18%,DAM:96.21%,DFLX:98.91%,OFL:99.37%,NOR:99.31%,LOM:98.09%,and the CIP:98.68%.