The Fabrication Of Functionalized,Multi-morphology Mesoporous Carbon Materials And Their Research On Drug Release And Dye Adsorption

Mesoporous carbon materials continue to be a focus of rapid innovations due to their unique intriguing characteristics,such as good thermal stability,high surface area and large interior space,ensuring promising potentials in adsorption,separation and sensor technology.To further improve performance of mesoporous carbon materials,extensive research efforts have attempted to functionalize mesoporous carbon materials,such as integrate nitrogen atoms and magnetic nanoparticles into mesoporous carbon materials.Up to date,organic-organic self-assembly is one of the most commonly used methods for preparing mesoporous carbon materials.Unfortunately,control of morphology,size,and uniformity in mesoporous carbon is much more difficult.Moreover,due to weak interactions between the carbon precursors and soft templates,the mesoporous structure of carbon materials always suffered collapses,which may limit their further applications in the adsorbents and drug delivery.In this study,based on the enhanced hydrogen-bonding interaction,we concentrated on the synthesis of monodispersed N-doped mesoporous carbon nanospheres?NMCNs?with tunable sizes and unprecedented amount of nitrogen via a facile one-pot self-assembly strategy.By engineering the compositional diversity inside the single nanoparticles,monodispersed Fe₃O₄-nanoparticles were introduced into the NMCNs via the interactions between-NH groups and iron ions.The mesoporous carbon nanospheres with superparamagnetism were prepared successfully.In addition,after introducing the silicon source and adjusting the relevant experimental parameters,a series of multi-morphological mesoporous carbon materials including orchid-like?OHPC-25?,fibrous and spherical were synthesized for the first time.In this paper,two insoluble drugs,albendazole and itraconazole,were selected as model drugs to investigate the drug release properties of NMCNs and OHPC-25,respectively.At the same time,acid red 57 was selected as the dye to investigate the adsorption properties of magnetic mesoporous carbon nanospheres.The main research of this paper were as follows:?1?NMCNs with rich N content were fabricated via a one-pot self-assembly strategy by using phloroglucinol-formaldehyde?PF?as the carbon precursors.ethylenediamine?EDA?was used as both a catalyst and nitrogen precursor,while F127 as a template.The study found that the experimental variables such as EDA concentration,carbon precursor type and hydrothermal reaction have great influence on the size uniformity,particle size and morphology of carbon nanospheres.Moreover,the high hydroxyl density in the oligomers formed from phloroglucinol and formaldehyde could provide greater driving force for the self-assembly interaction with the PEO segments of the F127 through strong hydrogen bonding interactions,which addressed the problem of weak self-assembly ability between the usual carbon precursor and template.Thus ensuring the successful fabrication of NMCNs with rich nitrogen.After the albendazole was loaded into the mesoporous carbon nanosphere,the drug release ability was improved significantly.?2?Metal nanoparticle-decorated mesoporous carbon spheres were prepared by combining one-pot aqueous synthesis and post-synthesis modification.The-NH groups on the carbon nitride can provide an anchoring and heterogeneous surface,thus allowing the formation of highly dispersed metal nanoparticles.In addition,it is found that with the increase of iron content,the morphology of mesoporous carbon nanospheres changed from sphere to amorphous and rod.Acid red 57 was used as a model dye to explore the adsorption properties of magnetic mesoporous carbon spheres.The results show that the magnetic mesoporous carbon sphere could adsorb the dye efficiently in the water.?3?Using tetraethyl orthosilicate as the silicon source,phloroglucinol as the carbon source and EDA as the catalyst,the polymorphic mesoporous carbon materials such as orchid,spherical and fibrous were synthesized under the treatment of acetone.It has been found that adjusting the concentration of acetone could achieve a change in the morphology of mesoporous carbon materials.When the acetone concentration was constant,the hollow carbon nanospheres could be synthesized efficiently by changing the amount of silicon source in the reaction system.In addition,the study also examined the morphology changes of mesoporous carbon in different reaction periods.The obtained orchid-like mesoporous carbon material has a high specific surface area,and thus increased the release ability of the poorly soluble drug itraconazole.