Extraction Of "Astragalus-Angelica" Elevated White Blood Cell Parts Study On Technology And Quality Standards

Application compatibility of "Astragalus-Angelica" has quite a long history,the book chronicles both the compatibility and application of traditional Chinese medicine in past dynasties in China used to airlift the case a lot of blood.Huangqi danggui buxue Tang is the most classic is also one of the most commonly used formulae,only two kinds of Chinese herbs,namely,astragali and Angelica.Modern treatment with this side of both Qi and blood loss due to the weak.Along with the development of modern pharmacology,we find "Astragalus-Angelica" compatibility with strong immune systems,compatibility of the two can effectively increase white blood cells.Today,cancer radiotherapy,chemotherapy,chronic hepatitis and other causes of leukopenia caused by rising incidence and modern Western medicine for this card without any special treatment,Chinese medicine they would stand out in this regard.TCM leukopenia are designated as "deficiency" category,and the compatibility of astragalus-Angelica is the main effect of buqi liters of blood,it does in treating leukopenia with significant results.This topics to "Astragalus-Angelica" compatibility elevated white cell parts for points,tries to optimization out "Astragalus-Angelica" of best extraction technology,research in the innovation used its on by ring phosphorus n amine made die small rat elevated white cell of Pharmacology effect as quality standard,used orthogonal test design,on plus water,and fried Cook time,and soaking time and extraction number four a factors for research,according to L9(34)orthogonal table visits,should two species evaluation indicators,eventually determines best water fried Cook technology.In terms of quality standards research,qualitative,respectively of astragalus membranaceus and Angelica sinensis by thin-layer chromatography,and choose the best agent,experimental results show that the chromatogram separation is good;in extracts by high performance liquid chromatography for determination of ferulic acid,method validation.Finally for fingerprints of the establishment,through the "Astragalus-Angelica" for testing liquid samples and reference substance by HPLC fingerprinting,identifying common,verify that the total of the relative retention time of peak and good reproducibility of relative peak area;and peak characteristic peaks attribution analysis.Research in the u elected "Astragalus-Angelica" elevated white cell parts extraction technology,and through on its for quality standard of research confirmed the technology stable viable;quality standard in the the indicators of check method by party law research indicates that reproduce sexual good,and stability high,can for "Astragalus-Angelica" elevated white cell parts extraction technology of quality control;on "Astragalus-Angelica" drug on for fingerint Atlas of established,analysis peak belonging,for future this drug on elevated white cell parts of thoroughly separation extraction,Preparation to theory basis for the long-term stability of formulations of medicines.