The Studies Of Oxidizing Reaction In The Air With Ruthenium Catalyst And Its Application In The Synthesis Of Benzoic Esters And Alkenes Cyanide Compounds

The thesis was focused on researching the oxidation reactions in the aerobic conditions with ruthenium catalyst.We served a novel and convenience method of making benzoic esters and alkenes cyanide compounds.Their advantages were short reaction steps,highyield,substrate spectral width.moreover,the way could extend the catalytic reaction type,enrich the ruthenium organic chemistry.First,using ruthenium catalyst,the thesis studied the method and mechanism of the reaction of the preparation of benzoic esters through oxidizing aryl-acetonitrile compounds and hydroxyl compounds.This part,we studied the rate of charge,catalyst dosage,reaction time,temperature,solvent and the choosing of substrates,by which we optimized the reaction condition.At last,we predicted the possible mechanism of the preparation of benzoic esters reaction.Second,using ruthenium catalyst,the thesis studied the method of the Knoevenagel reaction without base.The C-H of methylene compound can be activated by the ruthenium catalyst without base,then it combined with aldehyde or ketone to alkenes cyanide compounds.This part,we studied the rate of charge,catalyst dosage,reaction time,temperature,solvent and the choosing of substrates,by which we optimized the reaction condition.At last,we predicted the possible mechanism.Third,this thesis found ruthenium can catalyze the reaction of aryl-acetonitrile compounds with methyl cyanoacetate to alkenes cyanide without base.Ruthenium can also catalyze the reaction of aryl-acetonitrile compounds with themselves to alkenes cyanide with base.This part,we studied the rate of charge,catalyst dosage,reaction time,temperature,solvent and the choosing of substrates,by which we optimized the reaction condition.At last,we predicted the possible mechanism.