| The optical perproties of the noble metal nanoparticles and their assamblies,such as SPR and SERS,are of great applications in the biomedical field.Using the FDTD to simulate the SPR signal and field distribution of the noble metal nanoparticles,we can analyze accurately the LSPR shift and SERS changes.The FDTD results can vertify the experiment and be a guider for the development of experiment.This arcticle introduces what are FDTD and FDTD Solutions,and the steps of modeling in the first several paragraphs.Then it focus on the study of these simulations whose themes are based on Au@AgNC.First one is the individual Au@Ag core-shell nanocube(Au@Ag NC)modified with tetrahedron-structured DNA.An average localized surface plasmon resonance(LSPR)scattering spectral wavelength shift of can be obtained for a single miR-21 hybridization event on the nanobiosensor.Second one is the individual Au@Ag core-shell nanocubes(Au@Ag NCs)and varisized gold nanospheres(GNSs)conjugated via the biotin-streptavidin interaction from the ensemble to the single-assembly level to fabricate the controllable self-assembled hot spot.In addition,two simulations of other models were done.First one is the etching of the Au nano triangle sheet and the LSPR shift during the etching process was measured,which can be used to detect the concentration of the H2O2.Following one is an exploratory simulation.Several Au nano particles was assembled around the Au@Ag core-shell particle(Au@AgNP).Changing the assembly distance between the surrounding particles and the core Au@AgNP and the amount of these distance-changing surrounding particles to study the change of the SERS of these structures. |