Dual-Channel Mutual Injection Laser And It's Application In Microstructure Processing Of Drug-Carrying Coronary Stent

The use of drug-eluting stents for coronary artery stenosis is currently the most effective method for treating coronary heart disease.The micro-nano structure on the surface of the stent determines the number and type of drugs carried,how to prepare a uniform micro-nano structure on the surface of the coronary stent is a hot issue at present.Multi-beam laser interference processing technology is widely used to prepare micro / nano structures on the surface of scaffolds due to its characteristics of being able to process large-area micro / nano structures on non-planes.In previous multi-beam interference experiments,a single beam was output by a laser,and the beam was split and reflected by a plurality of beam splitters and reflectors to form four beams and intersect.Too many beamsplitters and reflectors make the processing system complicated,low reliability,and easily misaligned,multiple reflections make the final light spot larger and the interference pattern is not ideal.This paper studies the operating mechanism of a dual-channel inter-injection laser,a dual-channel inter-injection solid-state laser based on a U-cavity structure is constructed,after performing intra-cavity electro-optical Q-switching,two parallel beams of 186 mJ and 8.2ns pulse width are output.Through theoretical analysis and software simulation of laser interference,the experimental parameters of interference processing were determined,and then a non-coplanar four-beam laser interference processing system was built using a dualchannel inter-injection solid-state laser as a light source to perform four-beam interference processing on the surface of the coronary stent.When the incident angles are 22°,9.7°,and 6.2°,micro-nano structures with a cycle of 2.06?m,4.58?m,and 7.07?m are processed,which are basically consistent with the graphics simulated by software.The experimental results show that the dual-channel inter-injection solid-state laser built in this paper is used as a light source for four-beam laser interference processing,which not only facilitates the adjustment of the experimental optical path,ensures experimental reliability and shortens the experimental time,but also solves the interference pattern caused by too many beam splitters,the system is susceptible to imbalance,it can process micro-nano structures with uniform cycles on the surface of the stent,and provide samples for subsequent drug-loading experiments,which has a positive significance for micro-nano processing technology.