Study On ERP Characteristics Of Normal Young People With Pure Tone And Different Stimulation Modes At Different Frequencies

Objective: Auditory event-related potentials(AERP)tests were performed on young people with normal hearing using different frequencies of pure tone and different stimulation modes.The waveforms of ERP and the distribution of brain topographic maps during brain processing of different frequencies were discussed.The law of change,in order to provide a basis for the objective assessment of the cognitive function of sound perception,discrimination and recognition.Methods: 30 cases with normal hearing young adults were selected,record every subjects binaural auditory event-related potentials under different frequency acoustic stimulation and different stimulation modes.Test modes include monophonic stimulation,two-tone stimulation,and three-tone stimulation: monophonic stimulation is stimulated with 0.5 kHz and 1.0 kHz short pure tones;the two-tone stimulus is Oddball mode,with 0.5kHz or1.0kHz short pure tone as target stimulation,and 2.0kHz short pure tone as standard stimulus;the three-tone stimulus is the Oddball dual-task mode,with 0.5kHz and 1.0kHz short pure tone as the target stimulus,and 2.0kHz short pure tone as the standard stimulus.The waveform characteristics and brain topographic features of ERP components induced by different frequencies in different stimulation modes and by different frequency stimulation under different stimulation modes were compared and analyzed.Results: 1.The results of the three-stimulus ERP-induced traceability analysis show that the neural impulses induced by acoustic signals are transmitted between brain regions: cerebral palsy(T7),central brain region(Cz),frontal region(Fz),and Top area(Pz).2.Mode of monophonic stimulation: The pure frequencies of the three frequencies only induced P1,N1 and P2 waves,and there was no difference between the three waves(p>0.05).3.Mode of the two-tone stimulus: Standard stimuli induced P1,N1,and P2 waves,and target stimuli induced P1,N1,P2,N2,and P3 waves.The N1 and P2 latency induced by standard stimulation was longer than the target stimulus(p<0.05),the amplitude was lower than the target stimulus(p<0.05),and there was no difference between the target stimulation and the N1 and P2 waves(p>0.05).4.Mode of the three-tone stimulus: Standard stimuli induced P1,N1,and P2 waves,and two target stimuli induced P1,N1,P2,N2,and P3 waves.The N1 and P2 latency induced by standard stimulation was longer than the target stimulus(p<0.05),the amplitude was lower than the target stimulus(p<0.05),and there was no difference between the target stimulation and the N1 and P2 waves(p>0.05).5.The amplitudes of N1 and P2 induced by 2000 Hz pure tone in sensory mode are higher than that of discrimination and recognition mode(p<0.05),and the latency of P2 is better than that of discrimination and recognition mode(p<0.05).6.The N2 and P3 amplitudes induced by pure tone stimulation in the discrimination mode are higher than the recognition mode(p<0.05).Conclusion: 1.The three-stimulus ERP-induced traceability results suggest the sequence of nerve impulses generated by acoustic signals in the brain region.According to the ERP traceability results,the cortical auditory dysfunction can be determined and judged in forensic science.2.The late ERP components induced by pure tone and different stimulation modes at different frequencies can determine whether the subjects have the ability to distinguish and recognize pure tones of different frequencies.The late components are also related to the degree of difficulty of selecting and the difficulty of different stimulation modes to some extent.