Study On The Related Factors Of HIV Infection And Drug Use In Men Who Have Sex With Men In Harbin

Objective:To investigate the status and risk factors of HIV infection among men who have sex with men(MSM)in Harbin,and to study the use of drugs and related factors in the MSM population.Methods:From April 2016 to April 2017,we recruited MSM for cross-sectional studies in various ways in Harbin.Potential MSM participants are invited to participate in the free HIV and syphilis test registration on the premise that they participate in online questionnaires to collect information about MSM HIV-related infections and drug use.Multivariate logistic regression analyses were used to determine the factors associated with HIV infection and the relationship with drug use.Results : The prevalence of HIV among the 6,710 MSM was 8.5%,the prevalence of syphilis was 6.4%,and the average age was 31.6±10.3 years.Among them,the education level was 46.3% for universities and above,and the marital status was unmarried MSM.MSM used occasional or never used condoms accounted for 34.5%.There were 822 MSM who had had an HIV test in the past 12 months,accounting for 12.3%.There were 1547 drug users,accounting for 23.1% of the total survey population.Of these,1283(19.1%)used Poppers and 215(3.2%)used illegal drugs.This study shows that the older the higher the risk of HIV infection(relative to the age of less than 25 years,26-35 years old: OR = 1.3,95% CI: 1.0-1.6;36-45 years old: OR = 1.5,95% CI: 1.1-2.0;greater than 45 years old: OR = 1.7,95% CI: 1.2-2.4);The higher the level of education is,the lower the risk of HIV infection(OR = 0.6,95% CI: 0.5-0.7);Divorced or widowed HIV infection risk is 1.7 times married people(OR = 1.7,95% CI: 1.2-2.5);Occasionally or never using condoms is 1.5 times more likely to use HIV than someone who frequently used or used it every time(OR = 1.5,95% CI: 1.2-1.8);the higher the number of HIV tests in the past 12 months,the lower the risk of HIV infection(detected once,OR = 0.7,95% CI: 0.6-1.0;testing 2 times and Above,OR = 0.4,95% CI: 0.2-0.7);and the HIV risk of MSM with more frequent HIV tests in the past month was 1.7 times that of non-detectors(OR = 1.7,95% CI: 1.2-2.5);The risk of HIV infection among those who have never received sexually transmitted diseases is 1.4 times that of those who have been tested(OR = 1.4,95% CI: 1.1-1.8);the HIV risk of those who are positive for syphilis is 5.4 times that of syphilis-negative individuals(OR = 5.4,95% CI: 4.2-7.0).The results of this study show that people who use Poppers have a 1.8 times higher risk of HIV infection than those who do not use any drug(OR = 1.8,95% CI: 1.5-2.3).The results of multivariate regression analysis showed that "Poppers" personnel were more likely to be younger(OR=2.3,95% CI: 1.8-3.0 for 30 years of age,and OR=2.0 for 31-40 years),as opposed to the ?do not use drugs? group.95% CI: 1.6-2.6),high education(OR = 1.3,95% CI: 1.1-1.5),unmarried(OR = 1.4,95% CI: 1.2-1.7),divorced or widowed(OR = 1.6,95 %CI:1.2-2.4),the number of HIV tests in the past year was more than one(OR = 1.9,95% CI: 1.6-2.3;twice and OR = 2.0,95% CI: 1.5-2.6),was diagnosed as Sexually transmitted diseases(OR = 2.7,95% CI: 2.0-3.6)are more likely to be infected with HIV(OR = 1.8,95% CI: 1.5-2.3)and more susceptible to syphilis(OR = 1.3,95% CI: 1.0-1.7).Conclusion: Poppers are more commonly used in the MSM population.Using poppers,high-risk sexual behavior and syphilis infections significantly increase the risk of HIV infection in Harbin MSM.It is recommended that relevant policy makers add poppers to the list of officially controlled illegal drugs in order to reduce HIV transmission among MSM communities.In addition,a comprehensive strategy should be implemented to control their high-risk sexual behavior and the risk of syphilis infection.These may require new ways to prevent HIV infection with MSM.