Research On Coupled Bionic Anti-adhesion Property Of Minimally-invasive Electrosurgical Electrode

In a variety of minimally invasive operations,the most common is to perform electrosurgical operations under high frequency electric current,and minimally-invasive electrosurgical electrode is the most widely used.The high frequency electric knife uses the thermal effect of high frequency current and the skin effect to achieve the purpose of work.Carbonization of biological tissue occurred extremely easily because of the high temperature.The adhesion on the surface of minimally-invasive electrosurgical electrode leads to the failure of high frequency electric knife.In order to solve this difficult problem,only the carbonized tissue on the surface of the electrode can be erased,or the electrode is replaced frequently.The traditional solutions include single physical method and single chemical method.However,single modification cannot effectively solve the serious adhesion of tissues.Therefore,in this paper,a bionic micro/nano-structure and chemical coating were combined to prepare an efficient anti-adhesive minimally-invasive electrosurgical electrode.Perilla leaf,bamboo leaf and maize leaf were selected to determine their adhesion force by atomic force microscopy measurement.The results showed that the surface adhesion of the three kinds of leaves was ordered as follows:maize leaf<bamboo leaf<perilla leaf.So the maize leaf was chosen as a bionic prototype of coupled bionic high-frequency electrode,and a series of subsequent experiments were carried out.Following the principle of”structural optimization and functional prominence",the bionic design of minimally-invasive electrosurgical electrode surface is designed based on the mechanism of anti-adhesion of the maize leaf.According to the experimental design and optimization method,L9(34)orthogonal table was used to arrange 9 kinds of minimally-invasive electrosurgical electrode bionic morphology.The bionic morphologies of the minimally-invasive electrosurgical electrode surface were prepared by laser marking.Four butyl titanate,acetylacetone and absolute ethanol were selected as precursors,inhibitors and solvents,respectively,and the precursor solution of TiO2 was prepared by sol-gel method(sol-gel).The coating on the surface of the bionic electrode was carried out by the rotary coating method using the homogenizing machine.The prepared TiO2 gel was dripped onto the substrate,and the high-frequency electric knife was glued to the glass slide.The speed of the homogenizing machine was set to low speed 480r/min,and the coating time was set to 15s.The electric cutting tests were carried out with a S900E type high frequency electric knife.The fresh isolated liver tissue,muscle tissue and adipose tissue were derived from a pig which was slaughtered on the day.It can be seen very intuitively that the order of influence of three different factors on the adhesion properties of electrode surface is as follows:transverse ridges spacing>longitudinal ridges spacing>transverse longitudinal ridges width.The results showed that when the transverse and longitudinal ridge width were 100 m,the transverse ridge spacing is 500 m,the longitudinal ridge spacing is 1000 m,the anti-adhesive property of minimally-invasive electrosurgical electrode is the best.The regression equation is as follows:(?)=6.7899-0.0144z1-4.8×10-5Z12-0.0219z2+2.1×10-5z22+3.2×10-3z3-2.25×10-6z32The surface adhesion qualities of the coupled bionic electrode with the cutting time and the cutting depth were analyzed,respectively.The results showed that with the increasing of electric cutting time,the adhesion weight of electrode substrate and the coupled bionic electrode surface showed an upward trend.With the increasing of the cutting depth,the adhesion weight of the two kinds of electrode surfaces also showed an upward trend.However,the coupled bionic electrode not only has better anti-adhesion property,but also has a slower tissue adhesion speed than that of the electrode substrate.Compared with the minimally-invasive electrosurgical electrode substrate,the tissue adhesion to the surface of coupled bionic electrode has been reduced 71.43%.