Clinical Observation Of Non-drug Therapy For Parkinson's Disease

Objective:To explore the clinical efficacy of non-drug therapy(Ba Duan Jin exercise,Mediterranean diet,Five Elements music,acupuncture)for 24 weeks in patients with Parkinson's disease(PD).Methods:Cases of PD were selected from Dongzhimen Hospital and Beijing Hospital from May 2016 to March 2016.26 PD cases were finally included in the study,whose ages vary from 52 to 80.The 26 PD cases were randomly divided into non-.drug therapy group and control group.The non-drug therapy group was given to the non-drug therapy including Ba 'Duan Jin exercise,Mediterranean diet,Five Elements music and acupuncture,based on the basic.treatment;the control group was given the basic treatment.All groups were scored referring to Uniform Parkinson's Disease Rating Scale(UPDRS),Parkinson's Disease Non-motor Symptom Scale(NMSS)and Parkinson Fatigue Scale(PFS)at the baseline(0 week),mid-term(12 weeks),and endpoint(24 weeks).The efficacy of non-drug therapy was evaluated comprehensively by comparison between groups and before and after comparison within the group.SPSS 20.0 was used for statistical processing and analysis.The normality test was performed on the measurement data and expressed as "mean ± standard deviation".The normal distribution data was compared by the paired t-test before and after treatment and the independent t-test was used for comparison between two groups.The non-normal distribution data was compared by the relevant sample non-parametric test before and after treatment and the independent non-parametric test was used for comparison between two groups.The counting data was expressed in frequency(percentage),and the chi-square test was used for comparison between two groups.Results:The reduction rates of UPDRS score between two groups have no statistical difference(P=0.954),the reduction rates of NMSS score between two groups have no statistical difference(P=0.567),the reduction rates of PFS score between two groups have statistical difference(P=0.044),and the reduction rate of non-drug therapy group was higher than that of control group.Conclusion:Non-drug therapy(Ba Duan Jin exercise,Mediterranean diet,Five Elements music,acupuncture)combined with western medicine had obvious advantages to relieve fatigue symptom in patients with Parkinson's disease than taking western medicine alone.But there was no obvious advantage in improving the overall state of motor symptoms and non-motor symptoms in patients with Parkinson's disease.