| Objective:This study is aimed at preliminary discussion correlation between the FLAIR vascular hyperintensity(FVH)And Syndrome differentiation of traditional Chinese Medicine(TCM)and the degree of middle cerebral artery(MCA)stenosis and clinical disease severity and short-term prognosis in patients with acute cerebral infarction(ACI).Methods:A total of 81 cases of acute cerebral infarction were collected in patients with clinical data,laboratory examination and brain MRI and MRA(Observation of patients’cerebral infarction in the acute middle cerebral artery supply area by DWI,Observation of the appearance and the number of layers of the distal FVH in the acute middle cerebral artery supply area by FLAIR,to find if there is stenosis or not and the rate of stenosis of MCA).And according to the standard of TCM syndrome differentiation,the Daily living ability Barthel index scale for Chinese medicion Syndrome differentiation and daily living ability score(DLAS)(index of daily living ability at admission as an indicator of the severity of the patient’s condition;The difference between DLAS at admission and at discharge(improvement score)as an indicator of the patient’s short-term prognosis).Admission score was completed in the day of admission,discharge score was completed in the day of discharge,the laboratory examination after admission in second days,brain MRI and MRA were completed on the forth day of admission).81 patients with acute cerebral infarction were divided into two groups according to the skull MRI FLAIR sequence:positive FVH and negative FVH.Record data,set up database,SPSS21.0 software is used to analyze the data.2.Results:1.By the two groups of independent sample t test and chi square test,there were no significant difference between FVH and hypertension,diabetes,coronary heart disease,hyperlipidemia,atrialfibrillation,homocysteine(HCY),fibrinogen,hospitalization systolic pressure,hospitalization diastolic pressure,smoking and drinking(P<0.05).2.By the Rank sum test of hierarchical data,there was a statistical difference between FVH and the degree of vascular stenosis(P=0.021<0.05).FVH appeared mainly in the severe vascular stenosis and occlusion group,mild to moderate vascular stenosis group FVH proportion is low;by the analysis of ROC curve,FVH to determine the vascular occlusion with high accuracy(the area under the curve(AUC)=0.714,P=0.004<0.05).3.By the two groups of independent sample rank sum test,there was a significant difference in the improvement score between FVH group and non FVH group(P<0.05).The short-term prognosis scores of FVH group were significantly higher than that of non FVH group,so FVH had an important significance with the short-term prognosis of patients with acute cerebral infarction.4.Patients with FVH had higher admission scores than those without FVH,but by the two groups of independent sample rank sum test,there was no significant difference in admission score between FVH group and non FVH group(P>0.05).5.The frequency of syndrome differentiation in patients with acute cerebral infarction from many to few as wind phlegm and blood stasis resistance syndrome,Qi deficiency and blood stasis syndrome,Yin deficiency pneumatic syndrome,phlegmy heat astringing real syndrome,phlegmy wet god syndrome.by the chi square test,there was statistical significance in FVH group and non FVH group of Qi deficiency and blood stasis syndrome(P=0.004<0.005),so the frequency of FVH phenomenon in patients with Qi deficiency and blood stasis syndrome is low.FVH group and non FVH group of wind phlegm and blood stasis resistance syndrome was statistically significant(P=0.003<0.005),so the frequency of FVH phenomenon in patients with wind phlegm and blood stasis resistance syndrome is high.Conclusion:1.the presence of FVH was not associated with hypertension,diabetes,coronary,hyperlipidemia,atrial,fibrillation,homocysteine(HCY),fibrinogen,hospitalization systolic pressure,hospitalization diastolic pressure,smoking and drinking.2.There is a significant correlation between FVH and vessel stenosis grading.FVH is mainly found in severe stenosis and occlusion group.The proportion of FVH is low in patients with mild to moderate stenosis.FVH has a high accuracy in predicting vascular occlusion.3.FVH has an important significance with the good short-term prognosis of patients with acute cerebral infarction.The short-term prognosis scores in group FVH is significantly higher than those in the non FVH group.4.The scores of patients with FVH were higher than those without FVH,but there was no significant difference between the group FVH and the non FVH group in this study.5.The frequency of syndrome differentiation in patients with acute cerebral infarction from many to few as wind phlegm and blood stasis resistance syndrome,Qi deficiency and blood stasis syndrome,Yin deficiency pneumatic syndrome,phlegmy heat astringing real syndrome,phlegmy wet god syndrome.the frequency of FVH phenomenon in patients with Qi deficiency and blood stasis syndrome is low,but the frequency of FVH phenomenon in patients with wind phlegm and blood stasis resistance syndrome is high. |
