| Purpose:Experts in the world for the first time in China in 2016 " Metabolic inflammatory syndrome,(MIS)" concept,MIS is the Metabolic syndrome(Metabolic syndrome,MS)more suitable for Metabolic diseases,early screening,prevention and research.And the concept of MIS will promote different diseases has the same prevention methods and treatment.In this paper,through the comparative analysis respectively with MIS and without MIS and two groups of patients with type 2 diabetes with MIS group and associated with the MS group of data of patients with type 2 diabetes,At the same time analysis of type 2 diabetes relationship between TCM syndrome type distribution and MIS.Is beneficial to other metabolic disorders in patients with type 2 diabetes,early diagnosis and timely treatment.For chronic low-grade inflammation and the metabolic disease provide a basis for the further study.Understand the characteristics of TCM symptoms in the type 2 diabetes with MIS,For the syndrome of traditional Chinese medicine research and provide basis for clinical treatment based on syndrome differentiation..Material and method:In this paper,in August 2016-November 2016 in liaoning university of traditional Chinese medicine affiliated hospital endocrinology in patients with type 2 diabetes in hospital hospitalization data for analysis.To patients according to diagnostic criteria for type 2 diabetes and MIS can be divided into type 2 diabetes with MIS group and type 2 diabetes are not associated with MIS group,compared between two groups of patients age,duration of diabetes,body mass index(BMI),waist circumference(WC),C peptide(0,120min),Hemoglobin A1c(Hb A1c),blood lipids,inflammatory factors-c-reactive protein(CRP)and the associated with morbidity and complications of two groups of patients.Again according to the MIS will all of the patients and the diagnostic criteria for MS patients divided into with MIS and with MS group,analysis associated with morbidity and complications of two groups of patients was situation,and analysis of patients with type 2diabetes with MIS group composition and distribution characteristics syndrome of TCM types,basis for syndrome of TCM type groups,to compare the group between different syndrome types in patients with age,duration of diabetes,BMI,WC,C peptide,Hb A1 c,blood lipid,CRP and other three diseases except for type 2 diabetes accounted for.Application SPSS17.0analysis to the above information,count data by chi-square test,measurement data with mean±standard deviation((?) ± s)said,meet the normality and homogeneity of variance using single factor analysis of variance,nonparametric test does not meet the normality is used.Results:1.A total of 305 cases,155 cases of male,female 150 cases,the average age(60.67 ±12.35),the course of the disease in(9.87±7.58years).Among them with MIS group,246 cases of type 2 diabetes,accounting for 80.66%,without MIS group of 59 cases of type 2 diabetes,accounting for 19.34%.Type 2 diabetes with MIS group average WC(90.52 ±9.93cm)is greater than the type 2 diabetes without MIS group(82.78±9.75cm),significant statistical difference(P < 0.01);In patients with type 2 diabetes with MIS group C peptide 0 min,120 min C peptide,Hb A1 c values were higher than patients without MIS group,had significant statistical difference(P < 0.01),CRP,triglyceride(TG)is higher than in patients with type 2diabetes without MIS group,had significant statistical difference(P < 0.01),High density lipoprotein(HDL-C)lower than in patients with type 2 diabetes without MIS group,had significant statistical difference(P < 0.01),in the age?duration?cholesterol(CHOL)?Low density lipoprotein(LDL-C)on the differences between the two groups has no statistical significance(P ?0.05).2.Type 2 diabetes with MIS group the highest detection rate is hypertension 135 cases,accounting for 54.88%,followed by Diabetic peripheral neuropathy(DPN)of 107 cases(43.50%),74 cases of coronary heart disease,accounting for 30.08%,variable Diabetic kidney diseasesof(DKD)62 cases(25.20%),Diabetic retinopathy(DR)60 cases,accounted for24.10%,the lowest detection for cerebral infarction,46 cases,accounting for 18.70%.In patients with type 2 diabetes with MIS group is higher than the incidence of hypertension,cerebral infarction and DKD without MIS group,the difference statistically(P < 0.05),the incidence of coronary heart disease,DPN and DR,two groups of patients there was no statistically significant difference(P?0.05).3.Detection rate in patients with type 2 diabetes in MIS(246 cases,80.66%)was higher than MS detection rate(141 cases,accounting for 46.23%),the result has significant statistical difference(P<0.01);But the two groups of patients with coronary heart disease,cerebral infarction,DPN,DR,DKD detection rate,there was no statistically significant difference(P?0.05).4.Type 2 diabetes with MIS in group of four types of card type,the proportion of highest is qi and Yin deficiency and blood stasis type,83 cases(33.74%);Followed by wet and heat trapped,spleen and blood stasis syndrome in 81 cases,accounting for 32.93%;Again is two deficiency qi and Yin,43 cases,accounting for 17.48%;Is the minimum number of Yin and Yang deficiency and blood stasis type,39 cases,accounting for 15.85%.5.Type 2 diabetes with MIS in group of four types of card type,qi and Yin deficiency and blood stasis type and Yin deficiency and blood stasis type two is greater than the average age of patients with qi and Yin deficiency type and damp heat trapped spleen and blood stasis type patients,the difference was statistically significant(P<0.05);Patients with Yin deficiency and blood stasis type of course is greater than the other three syndrome types of patients,the difference was statistically significant(P < 0.05);Damp heat trapped and gas Yin deficiency of spleen and blood stasis syndrome in patients with type BMI were greater than both Yin and Yang deficiency and blood stasis type and qi and Yin deficiency and blood stasis type patients,the difference was statistically significant(P < 0.05);Damp heat trapped patients with spleen and blood stasis type WC value is greater than the other three syndrome types of patients,the difference was statistically significant(P < 0.05).6.Type 2 diabetes with MIS in group of four kinds of syndrome types,damp and hot trapped patients with spleen and blood stasis type C peptide 0 min value is higher than other three syndrome types of patients,the difference was statistically significant(P < 0.05);Qi and Yin deficiency type patient TG,CHOL,values are higher than that of qi and Yin deficiency and blood stasis type patients,the difference was statistically significant(P < 0.05);Hot and humid trapped patients with spleen and blood stasis type HDL-C value is lower than gas Yin deficiency and blood stasis type two patients,the difference was statistically significant(P <0.05);Patients with Yin deficiency and blood stasis type CRP value is greater than the other three syndrome types of patients,the difference was statistically significant(P < 0.05).Every syndrome type in LDL-C,C peptide 120 min,differences of Hb A1 c no statistical significance (P?0.05).7.In patients with type 2 diabetes with MIS groups,Other three diseases except in type 2diabetes is the highest proportion of atherosclerosis(AS),167 cases,accounting for 67.89%,followed by obesity,149 cases,accounting for 60.57%,the percentage is the least Non-alcoholic fatty liver diseases(NAFLD),105 cases,accounting for 42.68%.8.The MIS with one kind of disease,type 2 diabetes in 113 cases,accounting for 45.94%,with 2 kind of disease,85 cases,accounting for 34.55%,with 3 kinds of diseases,48 cases,accounting for 19.51%.Conclusion:1.MIS high detection rate in type 2 diabetes patients,more advantageous than the MIS recognition inflammation related metabolic diseases.2.The patients of type 2 diabetes with MIS by qi and Yin deficiency and blood stasis evidence type is given priority to;Qi and Yin deficiency type and damp heat trapped spleen and blood stasis type patients prone to obesity.Four TCM types of damp and hot easily trapped spleen and blood stasis patients with abdominal obesity;Yin deficiency and blood stasis type inflammation in patients with more obvious. |
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