Correlation Between TCM Syndrome Distribution Characteristics And Hcy In Patients With Non-valvular Atrial Fibrillation

Objective:To study the correlation between the distribution of Traditional Chinese Medicine(TCM)syndromes and homocysteine(Hcy)in patients with non-valvular atrial fibrillation.Methods:In this study,according to the development of "non-valvular atrial fibrillation in patients with TCM syndromes scale" collection of Beijing University of Traditional Chinese Medicine,Dong Fang Hospital,Department of Cardiology,March 1,2016 to March 31,2017 hospitalized patients with atrial fibrillation.TCM four diagnostic data and auxiliary examination,according to the inclusion and exclusion criteria,were selected for 118 patients with nonvalvular atrial fibrillation.The control group was followed by the principle of age stratification,and the patients were selected from August 1,2016 to September 30,2016,according to the order of admission,and 70 cases of non-atrial fibrillation were taken as the control group in the Department of Cardiology,Dong Fang Hospital of Beijing University of Traditional Chinese Medicine.The data were analyzed by SPSS21.0 statistical software.The count data were expressed as the number of cases(n)and the percentage(%).The X2 test was used to measure the data in the range of "X±S ",and the t test or Z test was used to P<0.05 for the difference was statistically significant.Results:1.Risk factors for non-valvular atrial fibrillation:hypertension,cerebrovascular disease in the atrial fibrillation group and the control group was statistically significant(P<0.05),Diabetes,coronary heart disease did not find correlation with atrial fibrillation;2.Distribution of TCM syndromes in patients with non-valvular atrial fibrillation:A prospective study of the distribution of TCM syndromes in 118 patients with nonvalvular atrial fibrillation was found that Qi deficiency and blood stasis(59 cases,50%)>Qi and Yin Deficiency(24 cases,20.3%)>phlegm and blood stasis(14 cases,11.9%)>yin deficiency with effulgent fire(7 cases,5.9%)>deficiency of heart-blood(5 cases,4.2%)>water-rheum intimidating the heart(4 cases,3.4%)>phlegm-fire confusing heart(3 cases,2.5%)>devitalization of heart yang(2 cases,1.7%).And clinical studies that the deficiency of blood stasis syndrome is common in patients with atrial fibrillation syndrome consistent.3.Relationship between non-valvular atrial fibrillation and left atrial diameter:The LAD between the atrial fibrillation group and the control group was statistically significant(P<0.05),indicating that LAD in patients with atrial fibrillation increased significantly.4.The relationship between homocysteine(Hcy)and non-valvular atrial fibrillation:The levels of plasma Hcy in 118 patients with nonvalvular atrial fibrillation were significantly higher than those in patients with nonvalvular atrial fibrillation(P<0.05),suggesting that Hcy and non-valvular atrial fibrillation have a certain correlation.5.There was no significant positive correlation between Hcy and LAD in patients with atrial fibrillation and corresponding LAD in 85 patients with elevated Hcy(>15?mol/L)(P>0.05).There was no significant positive correlation between Hcy and LAD in 41 patients with atrial fibrillation(AF)for more than one year(P>0.05).Conclusion1.Qi deficiency and blood stasis type is the most common type of TCM patients with non-valvular atrial fibrillation.2.There is a general increase in LAD in patients with nonvalvular atrial fibrillation.3.Patients with nonvalvular atrial fibrillation plasma Hcy levels were generally increased,suggesting that Hcy and nonvalvular atrial fibrillation have a certain correlation.