A Study With Analysis Of Clinical Risk Factors For Hyperthyroidism Heart Disease

Objective: The objective of the research is to investigate the clinical risk factors of hyperthyroidism heart disease and then provide a basic help for the early diagnosis and of disease.intervention.Methods: Collected 428 patients from January 2013 to December 2017 in Ningxia Medical University General Hospital,which included 157 cases of hyperthyroidesm heart disease,150 cases of simple hyperthyroidism,121 cases of healthy controls.Investegated the differences of these indexes between three groups,such as age,course of disease,white blood cell,neutrophile,lymphocyte,neutrophile to lymphocyte ratio,red cell width,free triodothyronine,free thyroxine,thyroid stimulating hormone,cholestero,triglyceride,creatine kinase,lactic dehydrogenase,and alpha-hydroxybutyrate dehydrogenase.Hyperthyroidesm heart disease was considered as the dependent variable and these clinical risk factors as the multiple independent variables,which were analyzed by the Logistic regression.Results:1.The most common arrhythmia in hyperthyroidism heart disease was atrial fibrillation,followed by ST-T change.The heart enlargement of HHD was mainly in the left heart.2.Compared with the hyperthyroidism group,the HHD group had a long disease course and an old age.There were significant differences between two groups(P <0.01).3.FT3,FT4 of HHD group were significantly higher than the control group,while TSH was significantly lower(P < 0.01).There were no statistical differences compared with hyperthyroidism group(P > 0.05).Analyzed by the logistic regression,FT4 was one of the major risk factors.4.White blood cell,neutrophile,lymphocyte of HHD group were significantly lower than the control group,there was significantly statistical difference(P < 0.01),while was no significance compared with the hyperthyroidism group.NLR was higer than the other groups(P < 0.01).Analysed by the logistic regression,NLR was one of the main risk factors.5.There was no statistical difference between the three groups in RDW,while analyzed by the logistic regression,it was one of the major risk factors.6.TC,TG decreased significantly in HHD group(P < 0.01).7.LDH,?-HBDH increased significantly in HHD group(P < 0.01),while ther was no statistical difference between three groups(P > 0.05).Conclusion:1.An old age,long duration were extremely important risk factors for HHD.2.The elevation of NLR,LDH,?-HBDH,FT4 were risk factos of HHD,and the early observing of them could help the diagnosisi and treatment.3.Low serum lipid level is a risk factor for HHD,and it is cruial to detect them early.