The Effects Of Early Pulmonary Rehabilitation Training On Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Used Non-invasive Mechanical Ventilation

Objective The purpose of this study was to evaluate the clinical effect of early pulmonary rehabilitation training on AECOPD patients with non-invasive mechanical ventilation,andtoexploretheimprovementofthequalityoflife,exercise endurance,dyspnea and hospitalization time.Methods 86 cases of AECOPD patients with non invasive mechanical ventilation were divided into the rehabilitation group and the control group according to the random digital table method,during the time from 2016 to 2018 year in the Department of respiration,Chengdu second people?s hospital.All of patients were treated with conventional medication and non-invasive mechanical ventilation.when the improvement of acute symptoms and after the appearance of pulmonary infection control window,the rehabilitation group started the pulmonary rehabilitation training twice a day,it was including respiratory training and exercise training.After rehabilitation training,the two groups were compared,including:arterial blood pressure?PaCO₂?,arterial oxygen pressure?PaO₂?,lung function FEV₁?FEV₁%pred?,chronic obstructive pulmonary disease test score?COPD assessment test,CAT?,modified British Medical Research Council?mMRC?,exercise ability test?30 seconds chair sitting test,30-STS?and hospitalization time.PaCO₂,PaO₂,FEV₁%pred,CAT,mMRC,30-STS were compared between the patients who received pulmonary rehabilitation training for 7 days and those who continued treatment for 7 days after the onset of acute symptom were improved and pulmonary infection control window were appeard.SPSS19.0 software was used for statistical analysis.Measured data with normal distribution were expressed as?X±S,and two independent samples t-test were used for comparison between groups.The counting datas were expressed in terms of frequency and percentage n?%?,and?² tests are used for comparison between groups.P<0.05 was considered statistically significant.Results?1?After the early pulmonary rehabilitation training,there was no significant difference in PaCO₂,PaO₂ and FEV₁%pred between the two groups?P>0.05?.Compared with the control group,the CAT scores of the rehabilitation group were significantly decreased?the rehabilitation group:13.40±2.28 scores,and the control group:15.03±2.96scores,P<0.05?,and the mMRC scores were significantly decreased?the rehabilitation group:1.83±0.54 scores,dan the control group:2.13±0.64 scores,P<0.05?,and the times of 30-STS were significantly increased?the rehabilitation group:10.68±1.62 times,and the control group:9.33±1.20 times,P<0.05?,and the hospitalization times were shortened significantly?the rehabilitation group:11.40±2.41 days,and the control group:12.58±2.50days,P<0.05?.?2?Compared with the control group,there were no significant differences in PaCO₂,PaO₂,FEV₁%pred,CAT scores,and mMRC scores in the rehabilitation group which had undergone the early pulmonary rehabilitation up to 7 days during the hospitalization period?P>0.05?.The times of 30-STS was significantly higher than that of the control group?the rehabilitation group:10.53±1.54 times,and the control group:9.44±1.31 times,P<0.05?.?3?no serious adverse events occurred during the whole early pulmonary rehabilitation training.Conclusions?1?The early pulmonary rehabilitation training can significantly improve the quality of life,increase exercise endurance,alleviate dyspnea symptoms and shorten the hospitalization time for the patients of AECOPD who had used non-invasive mechanical ventilation during the hospitalization period.?2?The starting point of early pulmonary rehabilitation training is safe for the patients of AECOPD who had used non-invasive mechanical ventilation after the improvement of acute symptoms and the appearance of pulmonary infection control window.