Evaluation Of Exercise Blood Pressure And Cardiorespiratory Tolerance In Elderly Hypertensive Patients

Background:Long-term exercise training can improve the body's heart and lung function,increase the effective circulation of blood flow and the body's oxygen carrying capacity,and thus improve the body's metabolic function and metabolic process.Exercise can lower blood pressure has been recognized by most studies,It is an important auxiliary means of non-drug treatment in patients with hypertension.Previous studies have mostly focused on patients with grade 1 or 2 hypertension and used exercise treadmill test to study.However,the study of cardiovascular response and cardiopulmonary function during exercise is relatively rare in patients with grade3 hypertension.Although hypertension patients get good antihypertensive effect after exercise,what are the risks of exercise and how is the cardiopulmonary function?This requires in-depth researches to discuss these issues that the physiological and physiological changes in the movement of hypertensive patients.This study will analyze the characteristics of exercise blood pressure changes in elderly hypertensive patients and non-hypertensive volunteers through cardiopulmonary exercise testing,and compare cardiopulmonary exercise parameters to assess cardiopulmonary tolerance,in order to provide an effective basis and guidance for the formulation of exercise prescriptions for elderly hypertensive patients.Methods:The patients with essential hypertension who were between the ages of 60-80years old and were undergoing a cardiopulmonary exercise test at the Second Affiliated Hospital of Nanchang University from September 2016 to February 2018.They were divided into groups of patients with hypertension grade 1?n=20??hypertension grade 2?n=20??hypertension grade 3?n=20?and elderly non-hypertensive volunteers?n=20?of the same age group were selected as the control group;Omron arm sphygmomanometer was used to measure the right brachial artery blood pressure and resting heart rate;BP-200plus automatic sphygmomanometer was used to monitor exercise blood pressure;CARDIOVIT AT-104 was used to monitor rhythm changes during exercise;A power bike was used to perform the Ramp exercise program,stop exercise after reach the indication of end of exercise,and then have a rest for 6 minutes,finally collect cardiopulmonary exercise-related parameters.Result:1?Hypertension groups and non-hypertension group in gender,age,height,weight,smoking,drinking,exercise,fasting glucose,Rest DBP,Rest HR,TG,LDL,HDL,LA,LV,RA,RV,LVEF had no significant statistical difference?P>0.05?;The difference of mass index,resting systolic pressure,resting pulse pressure,triglyceride,glycosylated hemoglobin compared with non-hypertension group was statistically significant.?P<0.05?;2?The levels of Rest SBP,AT SBP,Peak SBP,R2minSBP,R4minSBP and R6minSBP in hypertensive groups were significantly higher than those in non-hypertension group?P<0.05?.Significant differences between groups in hypertension?P<0.05?.The changes of pressure were consistent with systolic blood pressure;Rest DBP,AT DBP,Peak DBP,R2minDBP,R4minDBP and R6minDBP had no statistically significant difference between the groups?P>0.05?;3?High blood pressure during the exercise test and ST segment shift mainly occurs in the hypertension grade 2 group and hypertension grade 3 group,after the end of exercise to restore normal range;4?The parameters of cardiopulmonary exercise in the hypertensive groups compared with the non-hypertensive group were significantly different in terms of METs@peak,peak VO₂,peak VO₂/kg,peak VO₂%,the AT,AT VO₂/kg,the AT%,OUES,OUES/kg,O₂ pulse,VE@AT,VE@peak,VE/VCO₂ slope,P_ETCO₂,DP/RPP,BR@AT,the peak work rate,VO₂/WR slope?P<0.05?;No statistical difference between groups in RER@peak,BR@peak,and O₂ pulse%?P>0.05?.Conclusion:1?Hypertension patients are sensitive to changes in systolic blood pressure during exercise,and are more likely to experience high blood pressure and underlying risk of ST segment depression;diastolic blood pressure changes are relatively flat,with no significant difference;2?The cardiopulmonary tolerance in patients with hypertension was lower than that in non-hypertension group,and it was more obvious in patients with hypertension in grade 2 and 3;3?Steady blood pressure control in patients with grade 3 hypertension is still safe and effective at higher exercise intensity?4.8-6.8 MET?;...